OBJECTIVE The inclusion of the Community Health Index in the recording of National Health Service (NHS) contacts in Scotland facilitates national linkage of data such as prescribing and healthcare utilisation. This linkage could be the basis for identification of adverse drug reactions. The aim of this article is to report the views of healthcare professionals on data sharing, ownership and the...

OBJECTIVE To identify chromosomal regions that show evidence of linkage to age-associated hearing impairment (presbycusis) in humans. DESIGN We evaluated the genetic linkage between quantitative measures from audiometric examinations and markers from a genomewide scan in a population-based sample ascertained without respect to hearing status. PARTICIPANTS Audiometric examinations were condu...

Conventional wisdom suggests that the president’s standing with the public affects his success in Congress. Electoral self-interest is the primary reason to expect a relationship between presidential popularity and the behavior of members of Congress. Although numerous studies have analyzed the effects of presidential popularity, the lack of presidential approval data at the congressional const...

Basics of Linkage and Gene Mapping ......................................................................45 Linkage....................................................................................................................45 Linkage disequilibrium ............................................................................................47 Mapping functions ..............................

In 1962 the Committee on Prosthetics Research and Development authorized a survey of current orthotics research and development in a number of selected centers as an initial step in a proposed orthotics evaluation program. A prime purpose of the survey was the identification of orthotic devices and procedures as suitable subject matter for the evaluation program. One of the devices selected as ...

the incidence of pre-lingual hearing loss (hl) is about 1 in 1000 neonates. more than 60% of cases are inherited. non-syndromic hl (nshl) is extremely heterogeneous: more than 130 loci have been identified so far. the most common form of nshl is the autosomal recessive form (arnshl). in this study, a cohort of 36 big arnshl pedigrees with 4 or more patients from 7 provinces of iran was investig...