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نتایج جستجو برای Lipid Peroxidation

تعداد نتایج: 106150  
2000
EVA SÖDERGREN,

Södergren, E. 2000. Lipid peroxidation in vivo. Evaluation and application of methods for measurement. Acta Universitatis Upsaliensis. Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 949. 78 pp. Uppsala. ISBN 91-554-4791-0. Lipid peroxidation is thought to be an important factor in the pathophysiology of a number of diseases and in the process of ageing, but its me...

2011
Nidhi Gahalain, Jasmine Chaudhary, Ashok Kumar, Sunil Sharma, Akash Jain,

Lipid peroxidation (LPO) in cellular membranes is associated with changes in physicochemical properties and impairment of protein functions located in membrane environment. Recent studies shows involvement of LPO in biological signaling and various diseases. Lipids are oxidized by three distinct mechanisms: enzymatic oxidation; non-enzymatic, free radical-mediated oxidation and non-enzymatic, n...

Journal: :Physiological research 2004
M Krajcovicová-Kudlácková, V Spustová, V Pauková,

Levels of conjugated dienes of fatty acids (first peroxidation product) in relation to their substrates and promotors (triacylglycerols, homocysteine, iron) as well as to their inhibitors (essential antioxidative vitamins) were assessed in a vegetarian group (n=24) and compared with subjects on a mixed diet (traditional nutrition, n=24). Positive significant linear correlation between conjugate...

2017
Adil Raza, Sumit Kumar Varshney, Hiba Sami, Mohammad Jalal, Haris M Khan, Vaibhav Gupta, Ashraf Malik, M. Shahid, Abbas A Mehdi,

Objectives: Plasmodium vivax &Plasmodium falciparum are the important species causing malaria in Indian subcontinent. P. vivax usually causes uncomplicated malaria. Whatever be the cause of malaria weather P. falciparum or P.vivax, there is variable degree of oxidative stress. This oxidative stress leads to peroxidation of membrane lipids. Lipid peroxidation is measured in terms of metabolite m...

Journal: :Biochemical and biophysical research communications 2017
Michael M Gaschler, Brent R Stockwell,

Disruption of redox homeostasis is a key phenotype of many pathological conditions. Though multiple oxidizing compounds such as hydrogen peroxide are widely recognized as mediators and inducers of oxidative stress, increasingly, attention is focused on the role of lipid hydroperoxides as critical mediators of death and disease. As the main component of cellular membranes, lipids have an indispe...

2002
W. AGRANOFF,

This critique points out that a number of possible alterations in cell metabolism could lead to changes in membrane structure and that the observed effects might not necessarily play a primary role in the physiology of aging. Experimental approaches, while not simple, should distinguish causes of altered membrane asymmetry from its consequences. THE idea that cross-linking agents might play a r...

Journal: :Free radical research 2010
Anne Negre-Salvayre, Nathalie Auge, Victoria Ayala, Huveyda Basaga, Jordi Boada, Rainer Brenke, Sarah Chapple, Guy Cohen, Janos Feher, Tilman Grune, Gabriella Lengyel, Giovanni E Mann, Reinald Pamplona, Giuseppe Poli, Manuel Portero-Otin, Yael Riahi, Robert Salvayre, Shlomo Sasson, Jose Serrano, Ofer Shamni, Werner Siems, Richard C M Siow, Ingrid Wiswedel, Kamelija Zarkovic, Neven Zarkovic,

Lipid peroxidation (LPO) product accumulation in human tissues is a major cause of tissular and cellular dysfunction that plays a major role in ageing and most age-related and oxidative stress-related diseases. The current evidence for the implication of LPO in pathological processes is discussed in this review. New data and literature review are provided evaluating the role of LPO in the patho...

2005
Etsuo Niki, Yasukazu Yoshida,

Biomarkers are essential for assessment of oxidative stress and evaluation of antioxidant capacity in vivo. Total hydroxyoctadecadienoic acid (HODE)and7-hydroxycholesterol measured afterreduction and saponification ofbiological fluidsmaybeusedasreliablebiomarker. J. Med. Invest. 52 Suppl. : 228-230, November, 2005

Journal: :Acta medica Okayama 1995
H Iwagaki, K Hamazaki, N Matsubara, M Hiramatsu, K Orita, A Mori,

In this study, we measured free radicals and thiobarbituric acid-reactive substances (TBARS) in hepatocellular carcinoma and in non-cancerous liver parenchyma. There was a higher concentration of free radicals in malignant tissue than in non-cancerous tissue. In contrast, the level of TBARS was significantly (P < 0.01) lower than non-cancerous liver parenchyma. These paradoxical results suggest...

2014
Brigitte I Frohnert, David A Bernlohr,

Obesity-associated insulin resistance has long been linked to both increased adipocyte oxidative stress as well as the presence of inflammatory changes in adipose tissue, including the infiltration and activation of tissue-resident macrophages. In order to investigate the connections between obesity-associated oxidative stress in adipocytes and increased inflammation in adipose tissue associate...