A model for protein-lipid interactions in bilayer membranes where the proteins are very dilute is extended to higher protein concentration, where appreciable lipid-mediated protein-protein interactions occur. It is found that proteins may change the lipid phase transition temperature and that they weaken the phase transition. There exists a critical protein concentration above which the sharp l...

A 60-day trial with six diets (three different protein levels × two different lipid levels) containing 30, 35 and 40% protein with 10 and 15% lipid levels was conducted to determine the optimum dietary protein to lipid ratio and effects on growth performance and hematological indices of Aspikutum, Leuciscus aspius female×Rutilus frisii male. Two hundred and fifty two fish (31.2±0.4 g; mean±SEM)...

background: protein-protein interactions do not provide any direct information re­garding the domains within the proteins that mediate the interactions. the majority of proteins are multi domain proteins and the interaction between them is often defined by the pairs of their domains. most of the former studies focus only on interacting do­main pairs. however they do not consider the interaction...

Lung surfactant (LS) is an outstanding example of how a highly regulated and dynamic membrane-based system has evolved to sustain wealth structural reorganizations in order accomplish its biophysical function, as it coats stabilizes the respiratory air-liquid interface mammalian lung. The present review dissects complexity structure-function relationships LS through updated description lipid-pr...

Lipid-protein interactions in membranes are dynamic, and consequently are well studied by magnetic resonance spectroscopy. More recently, lipids associated with integral membrane proteins have been resolved in crystals by X-ray diffraction, mostly at cryogenic temperatures. The conformation and chain ordering of lipids in crystals of integral proteins are reviewed here and are compared and cont...

Anionic lipids play a variety of key roles in biomembrane function, including providing the immediate environment for the integral membrane proteins that catalyze photosynthetic and respiratory energy transduction. Little is known about the molecular basis of these lipid-protein interactions. In this study, x-ray crystallography has been used to examine the structural details of an interaction ...

To Sanni 5 CONTENTS ABBREVIATIONS 8 LIST OF ORIGINAL PUBLICATIONS 10 SUMMARY 11 1. REVIEW OF THE LITERATURE 13 1.1. Biological membranes 13 Structure and composition 13 Dynamics and organization 13 1.2. Lipid dynamics 15 Intra-and intermolecular dynamics 15 Lateral pressure profile 16 Lipid bilayer as a permeability barrier 17 1.3. Membrane hydration 18 1.4. Membrane lateral heterogeneity 19 1....