Saposin C (sapC) is a lysosomal, peripheral-membrane protein displaying liposome fusogenic capabilities. Proteoliposomes of sapC and phosphatidylserine have been shown to be toxic for cancer cells are currently on clinical trial treat glioblastoma. As proof-of-concept, we show two strategies enhance the applications proteoliposomes: (1) Engineering chimeras composed modulate proteoliposome func...

the object of this study was detecting protein and lipid contents on two types on iranian oncorhynchus mykiss & franciscan oncorhynchus mykiss for detect better samples on quality. in this research two methods were used for determining lipids (suxeleh) and proteins (kajheldal). results have revealed the lipid contents in iranian samples were 4.88 , 5.18 and 5.96 and in franciscan samples were 4...

The lipid bilayer component of biological membranes is important for the distribution, organization, and function of bilayer-spanning proteins. This regulation is due to both specific lipid-protein interactions and general bilayer-protein interactions, which modulate the energetics and kinetics of protein conformational transitions, as well as the protein distribution between different membrane...