Non-alcoholic fatty liver disease is one of the most important causes of liver-related morbidity in children. In non-alcoholic fatty liver disease, the activation of liver resident macrophage pool is a central event in the progression of liver injury. The aims of the present study were to evaluate the polarization of liver macrophages and the possible role of Wnt3a production by macrophages in ...

Monocytes and macrophages belong to the mononuclear phagocyte system play important roles in both physiological pathological processes. The cells belonging monocyte/macrophage are structurally functionally heterogeneous. Several subsets of monocytes have been previously identified mammalian blood, generating different subpopulations tissues. Although their distribution phenotype similar human c...