نتایج جستجو برای: Mesobuthus eupeus venom
تعداد نتایج: 9567 فیلتر نتایج به سال:
In tropical and subtropical countries, envenomation by scorpions (so-called scorpionism) represents a serious public health problem. In the present study, the toxic effects of mice LD50 injections of Mesobuthus eupeus (Me) venom on the kidney and liver of anesthetized rabbits were investigated. Six rabbits were selected and ALT, AST, BUN and creatinine were measured at 0, 1 and 3 hours after...
Background Many elements such as immunosuppressive, chemotactic and anti-inflammatory peptide that could effect on human and animals physiologic system were determined in venom. This study evaluated the use of Mesobuthus eupeus scorpion venom fractions as an immunomodulator. Methods The venom fractions collected from Khuzestan Province in South West of Iran were purified by ion exchange chrom...
background: the mesobuthus eupeus scorpion venoms are known to contain α-toxin peptides, many of which interfere with k+ ion channel function. these toxin peptides have important value in the pharmacology and physiology studies of specific k+ channel of cells. objectives: given the lack of information of the molecular biology of peptides in the toxin of iranian scorpions, the aim of this stud...
Iranian scorpions belong mainly to the Buthidae and Scorpionidae families, distributed into 16 genera and 25 species. In Iran, similar to other parts of the world, there are a few known species of scorpions responsible for severe envenoming; amongst which Mesobuthus eupeus is the most common. Its venom contains several toxin fractions that may affect the ion channel. In the present study purifi...
this study evaluated the effects of mesobuthus eupeus (me) scorpion venom on inflammatory response following injection. additionally, the present study examined whether immunotherapy at specific time intervals would be effective on inflammatory response after me venom inoculation. animals were divided randomly into four groups: the first group received ld50 of venom and the second and third gro...
background: immunotherapy is the only specific treatment for scorpion envenomation. in the present study, the protective effects of polyvalent antivenom against histopathological complications in kidneys and marker changes (bun and creatinine) induced by mesobuthus eupeus (me) scorpion venom was investigated in anesthetized rabbits. methods: twenty four rabbits were randomized into four groups:...
Scorpions are generally an important source of bioactive components, including toxins and other small peptides as attractive molecules for new drug development. Mesobuthus eupeus, from medically important and widely distributed Buthidae family, is the most abundant species in Iran. Researchers are interesting on the gland of this scorpion due to the complexity of its venom. Here, we have analyz...
in tropical and subtropical countries, envenomation by scorpions (so-called scorpionism) represents a serious public health problem. in the present study, the toxic effects of mice ld50 injections of mesobuthus eupeus (me) venom on the kidney and liver of anesthetized rabbits were investigated. six rabbits were selected and alt, ast, bun and creatinine were measured at 0, 1 and 3 hours after...
background: to explore the oral absorption of scorpion venom an elisa were designed in this study. scorpions and their venom were been used for centuries as medical treatments in traditional medicine. the oral administration of drug referred as the convenient way, as there was not any publication about gastro-intestinal absorption of scorpion venom; this experiment checked oral absorption of me...
objectives in this study, we reported the identification of a cdna sequence encoding cysteine-free antimicrobial peptides isolated from venomous glands of this species. materials and methods total rna was extracted from the iranian mesobuthus eupeus venom glands, and cdna was synthesized by using the modified oligo (dt). the cdna was used as the template for applying semi-nested rt- pcr techniq...
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