نتایج جستجو برای Modification

تعداد نتایج: 86422  

Journal: :The Journal of antibiotics 1995
S Bobillot, T Bakos, P Sarda, T T Thang, L Ming, A Olesker, G Lukacs,

20-Homo tylosin, 20-nor tylosin, 20-deoxy-19,20-didehydro tylosin (6-vinyl tylosin) and 2",3"-didehydro-3"-deoxy tylosin were prepared by multi-step procedures. 20-Homo tylosin was about twice less active than tylosin while the other compounds exhibited very weak antibacterial activity.

2012
R. Murali Shankar, M. Anoop, T. Harish, A. K. Rohit Prasad, A. G. Ramakrishnan,

In this paper, we propose a novel algorithm for pitch modification. The linear prediction residual is obtained from pitch synchronous frames by inverse filtering the speech signal. Then Discrete Cosine Transform (DCT) is applied on these pitch synchronous frames. Based on the desired factor of pitch modification, the dimension of the DCT vector is changed by truncation or zero padding, and then...

Journal: :Annual review of biochemistry 2004
Erica S Johnson,

Small ubiquitin-related modifier (SUMO) family proteins function by becoming covalently attached to other proteins as post-translational modifications. SUMO modifies many proteins that participate in diverse cellular processes, including transcriptional regulation, nuclear transport, maintenance of genome integrity, and signal transduction. Reversible attachment of SUMO is controlled by an enzy...

Journal: :Circulation 1971
J P Boineau,

To the Editor: The article by Maroko and his co-workers entitled "Factors Influencing Infarct Size Following Experimental Coronary Artery Occlusions" (Circulation 43:67, 1971) is indeed a very interesting one and an enthusiastic approach to the problem of modification of the size of an infarct. However, there are several points with regard to the methods that seem to need some clarification. Th...

2001
Victor J. Schoenbach, John Cassel,

The rise of the germ theory of disease brought with it the paradigm of specificity of disease causation, in which diseases were specific entities and each specific disease had a specific cause. Since identifiable microorganisms could be linked to specific clinical syndromes and natural histories, this paradigm contributed to the dramatic progress in medical microbiology and development of antib...

2007
Renata Vieira,

This paper presents the results of a corpus study which reveals the frequency of restrictive post-modification on definite descriptions in English language texts (newspaper articles). It shows that restricted descriptions are usually first mention uses (nonanaphoric) and that these can be systematically identified. The paper then compares features of restricted descriptions with bridging refere...

Journal: :Molecular cancer research : MCR 2003
David W Meek, Uwe Knippschild,

The functions of the MDM2 protein, in particular its E3 ubiquitin ligase activity and its ability to interact with a number of cellular proteins intimately involved in growth regulation, are modulated by sumoylation and multisite phosphorylation. These posttranslational mechanisms not only regulate the intrinsic activity of MDM2 in response to cellular stresses, but also govern its subcellular ...

2005
Ruwan P. Somawardhana,

Journal: :Nucleic acids research 1996
Pamela F. Crain, James A. McCloskey,

The RNA modification database provides a comprehensive listing of post-transcriptionally modified nucleosides from RNA and is maintained as an updated version of the initial printed report. Information provided includes: type(s) of RNA in which found and phylogenetic distribution; common chemical names and symbols; Chemical Abstracts registry numbers and index names; chemical structures; initia...

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