Amiodarone (AM) is a potent antidysrhythmic agent which can cause potentially lifethreatening pulmonary fibrosis, and N-desethylamiodarone (DEA) is a metabolite of AM that may contribute to the toxicity of AM in vivo. Recent evidence has implicated the involvement of the renin-angiotensin system (RAS) in the initiation and progression of amiodarone-induced pulmonary toxicity. In cultured HPL1A ...

BACKGROUND Dog erythrocyte antigen (DEA) 1.1 is the antigen considered most responsible for severe hemolysis owing to incompatible blood transfusions in previously sensitized dogs. Few reports describe the frequency of DEA 1.1 expression in European dogs, and there are no reports in dogs from Portugal. OBJECTIVE The aims of this study were to identify the frequency of DEA 1.1 expression in Po...

in this study, the relative performance of mazandaran wood and paper company as a major supplier of paper products in iran was measured. network data envelopment analysis (dea) models with parallel structure were used to evaluate and measure its performance. gams software version 23.4 was used for data analysis. results indicated that this company in all studied years had good performances base...

Diethanolamine-Induced Alteration of Hepatic Mitochondrial Function and Structure. BARBEE, S. J., AND HARTUNG, R. (1979). Toxicol. Appl. Pharmacol. 47,431-440. Diethanolamine (DEA) has been shown to interfere with phospholipid metabolism. It was hypothesized that DEA may alter membrane-bound biochemical processes which are dependent upon phospholipids. DEA was investigated for its effect on hep...

Data envelopment analysis (DEA), based on mathematical programming techniques, is a popular method for assessing the relative efficiency of various decision-making units (DMUs). Efficient DEA computations need to circumvent intensive time-consuming calculations. This paper indicates that the “corner points” in single input and single output scatter plot has extreme efficiency with regard to the...

Air freight network is one of the important means to improve the competitiveness of express enterprises. This paper establishes the model from two aspects, hub location decisions and hub number decisions, with the goal to achieve the lowest air freight network cost, based on the “hub-spoke” theory. Then, computes the cost of different number of hubs, and uses super-efficiency DEA model to decid...

0377-2217/$ see front matter 2012 Elsevier B.V. A http://dx.doi.org/10.1016/j.ejor.2012.03.043 ⇑ Corresponding author. Tel.: +1 613 533 6982. E-mail addresses: [email protected] (C. C [email protected] (J.-Y. Yu), [email protected] (H. Noori). 1 Tel.: +1 508 831 5467. 2 Tel.: +886 2 33661041. 3 Tel.: +1 519 884 0710x2571. Sustainable product design has been considered as one of the most impor...

Assessing the performance of Research and development (R&D) organizations to achieve higher productivity, growth, is always a critical necessity. Therefore, developing more accurate model evaluate required. For this purpose, study aimed at decision-making for evaluating R&D performance. The comes up with determining most proper evaluative criteria assessing organizations. Then, it integ...

The purpose of the present experiments was to test the hypothesis that diethanolamine (DEA), an alkanolamine shown to be hepatocarcinogenic in mice, induces hepatic choline deficiency and to determine whether altered choline homeostasis was causally related to the carcinogenic outcome. To examine this hypothesis, the biochemical and histopathological changes in male B6C3F1 mice made choline def...

The study aim was to establish the prevalence of DEA 1, the most immunogenic and clinically important blood group in canine blood transfusion, in 7,414 dogs from Italy. The potential sensitization risk following a first transfusion and the acute reaction risk following a second transfusion given without a cross-matching and blood typing test were also calculated. Dogs tested were purebred (4,79...