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نتایج جستجو برای Neuropathic pain

تعداد نتایج: 151423  
2012

Neuropathic pain results from damage to, or dysfunction of, the system that normally signals pain. The International Association for the Study of Pain (IASP 2007) defines neuropathic pain as follows: ‘Pain initiated or caused by a primary lesion or dysfunction in the nervous system. Peripheral neuropathic pain occurs when the lesion or dysfunction affects the peripheral nervous system. Central ...

2016
Junad Khan,

Neuropathic pain (NP) is defined as ''pain arising as a direct consequence of any lesion or disease affecting the somatosensory system. " [1,2] Although NP may be an idiopathic process reflecting abnormal sensory processing in the peripheral or central nervous system, it more often appears following physical insult or disease affecting the peripheral or central nervous system. It is likely that...

2003
John Scadding,

What is Neuropathic Pain? A limited understanding of underlying pathophysiology, and recent changes in terminology have led to some confusion. The International Association for the Study of Pain (IASP) defines NP as "pains resulting from disease or damage of the peripheral or central nervous systems, and from dysfunction of the nervous system". Originally, NP was used to describe only pain rela...

Journal: :Acta clinica Croatica 2009
Vanja Basić-Kes, Iris Zavoreo, Marijana Bosnar-Puretić, Mira Ivanković, Milan Bitunjac, Valbona Govori, Vida Demarin,

Neuropathic pain refers to pain that originates from pathology of the nervous system. Common causes of neuropathic pain are diabetes mellitus, reactivation of herpes zoster, nerve compression or radiculopathy, alcohol, chemotherapy or abuse of some drugs, and trigeminal neuralgia. Specific symptoms of neuropathic pain are mechanical allodynia and cold hyperalgesia. Drugs to treat neuropathic pa...

Journal: :Current opinion in neurology 2001
Eric Kerstman, Sangmin Ahn, Sree Battu, Shabrez Tariq, Martin Grabois,

Neuropathic pain is a clinical entity that presents unique diagnostic and therapeutic challenges. This chapter addresses the classification, epidemiology, pathophysiology, diagnosis, and treatment of neuropathic pain syndrome. Neuropathic pain can be distinguished from nociceptive pain based on clinical signs and symptoms. Although neuropathic pain presents a significant burden to individuals a...

Journal: :BMJ 2013
Eija Kalso, D J Aldington, R A Moore,

1Institute of Clinical Medicine, Faculty of Medicine, University of Helsinki, Pain Clinic, Department of Anaesthesia and Intensive Care Medicine, Helsinki University Central Hospital, PO Box 140, FIN-00029 HUS, Finland; 2Royal Hampshire County Hospital, Winchester, UK; 3Pain Research, Nuffield Division of Anaesthetics, Nuffield Department of Clinical Neurosciences, University of Oxford, The Chu...

2012
Wen Ren, Wenzhan Tu, Songhe Jiang, Ruidong Cheng, Yaping Du,

Applying a stimulating current to acupoints through acupuncture needles – known as electroacupuncture – has the potential to produce analgesic effects in human subjects and experimental animals. When acupuncture was applied in a rat model, adenosine 5’-triphosphate disodium in the extracellular space was broken down into adenosine, which in turn inhibited pain transmission by means of an adenos...

Journal: :European journal of pharmacology 2001
M Zimmermann,

This review deals with physiological and biological mechanisms of neuropathic pain, that is, pain induced by injury or disease of the nervous system. Animal models of neuropathic pain mostly use injury to a peripheral nerve, therefore, our focus is on results from nerve injury models. To make sure that the nerve injury models are related to pain, the behavior was assessed of animals following n...

Journal: :Pain physician 2012
Howard S Smith,

Opioids are broad spectrum analgesics that may be beneficial to alleviate the intense perception of algesia in patients suffering with pain. They have been one of the most controversial analgesics, in part because of their potential for addiction. Opioids or any currently available analgesic will not provide effective analgesia for every patient with chronic neuropathic pain (NP), but overall o...

Journal: :Mini reviews in medicinal chemistry 2003
P Goya, N Jagerovic, L Hernandez-Folgado, M I Martin,

After a brief overview of the endocannabinoid system (CB receptors, and endocannabinoids) and of the cannabinergic ligands, some general issues related to cannabinoids and pain are commented. Finally, the most important findings regarding cannabinoids and neuropathic pain are discussed in detail.