objective(s) the role of elaeagnus angustifolia fruit as an analgesic agent in acute pain has been proved earlier. in this study, the effects of aqueous extracts of three parts of this fruit (pericarp, medulla and seed) on chronic pain were investigated in mice. materials and methods a partial nerve injury was made using a tight ligature around the sciatic nerve, then doses (0.5, 1, 1.5 g/kg, i...

introduction: neuropathic pain may be due to a primary insult to the peripheral or central nervous system. in this situation, hyperalgesia and allodynia are the results of prostaglandins and cytokines release in the spinal cord. it seems that immune cells play an importat role in the induction and maintenance of chronic pain. compared to selective coxii inhibitors, nimesulide, a highly selectiv...

objectives this study investigates the prevalence of burning mouth symptom for the first time in an institutional group of patients in shiraz, iran, among whom some were found to have bms through excluding the recognizable physical or biochemical causes of mouth burning. methods in this cross sectional study, from the existing records of 2 533 patients who referred to shiraz dental school since...

Dr. Nijs et al (1) provided criteria for the classification of central sensitization (CS) pain. Peripheral neuro-pathic pain and nociceptive pain cause CS in the central nervous system if the 2 kinds of pain persist. Therefore, pure peripheral neuropathic pain and pure nociceptive pain are rare in clinical practice. I believe that CS is one of causes of central neuropathic pain. CS pain may be ...

Background Chronic neuropathic pain is a common occurrence, its prevalence ranges from 7 to 10% of the total population. Currently, only official document that includes International Classification Headaches Disorders (ICHD-3), in which this type associated with traumatic brain injury and neuralgia. Until now, there has been no generally accepted terminology classification chronic pain. Objecti...

INTRODUCTION Increasing evidence indicates that features suggestive of neuropathic pain may also be present in patients with common rheumatic conditions. The objective of this study was to examine neuropathic-like pain symptoms and associated factors in patients with rheumatoid arthritis. METHODS We used the painDETECT screening tool to identify possible or likely neuropathic pain in 159 outp...

OBJECTIVE To examine the profile and treatment pattern of patients with neuropathic pain attending Siriraj Pain Clinic. MATERIAL AND METHOD A 2-year retrospective study of the prevalence of neuropathic pain, characteristics of the patients and the use of medical treatment. Records of all the patients that attended Siriraj Pain Clinic from September 1, 2002 until September 30, 2004 were review...

BACKGROUND Neuropathic pain has been little studied in leprosy. We assessed the prevalence and clinical characteristics of neuropathic pain and the validity of the Douleur Neuropathique 4 questionnaire as a screening tool for neuropathic pain in patients with treated leprosy. The association of neuropathic pain with psychological morbidity was also evaluated. METHODOLOGY/PRINCIPAL FINDINGS Ad...