Background: The seeds of Nigella sativa plant have been used to promote health and fight disease for centuries especially in the Middle East and Southeast Asia. This plant has been a great focus of research. This clinical study was undertaken to determine the adjuvant effect of Nigella sativa oil on various clinical and biochemical parameters of the metabolic syndrome. Methodology: This prospec...

BACKGROUND Vitiligo is one of the autoimmune skin diseases that destroy the melanocytes of the skin. Moreover, its prevalence varies in different countries and regions. OBJECTIVES The aim of this study was to compare the effect of Nigella sativa and fish oil on vitiligo lesions of the patients referred to a dermatology clinic. MATERIALS AND METHODS This randomized, double blind clinical tri...

The present study was designed to investigate some histopathological changes produced by cimetidine on male reproductive organs (testes & epididymis) in mice and extended to examine wherethere using of aqueous suspension of powdered Nigella sativa seeds have ability to reduce this toxicity.Forty male mice were divided into 4 groups. The first group received 25 mg/kg B.W. of cimetidine orally on...

Black Seed The date and location of domestication of Nigella sativa is not clearly established, but the plant was certainly under wide cultivation more than 3000 years ago, when it was placed in the tomb of Egyptian King Tutankhamun. Historical evidence also shows contemporaneous, or earlier, black seed cultivation in Jordan and Iraq. In addition, wild types of Nigella sativa grow in Turkey, Sy...

UNLABELLED Diabetes mellitus is a common chronic disease affecting millions of people world wide. Standard treatment is failing to achieve required correction of blood glucose in many patients. Therefore, there is a need for investigating potential hypoglycemic drugs or herbs to improve glycemic control in diabetic patients. Nigella sativa seeds were used as an adjuvant therapy in patients with...

objectives: nigella sativa is a medicinal plant that has long been used in traditional medicine for treating various conditions. numerous animal studies provided evidences that the seed may elicit a broad anti-inflammatory/anti-oxidant activity. the aim of the present clinical trial was to evaluate anti-inflammatory and antioxidant properties of nigella sativa oil in patients with rheumatoid ar...

Hepatitis C is a major global health burden and Egypt has the highest prevalence of hepatitis C virus (HCV) worldwide. The current study was designed to evaluate the beneficial therapeutic effects of ethanolic extracts of Nigella sativa, Zingiber officinale and their mixture in Egyptian HCV patients. Sixty volunteer patients with proven HCV and fifteen age matched healthy subjects were included...

OBJECTIVE To determine the analgesic effect of ethanolic extract of Nigella sativa seeds on experimentally-induced pain in albino mice. STUDY DESIGN Randomized controlled trial (RCT). PLACE AND DURATION OF STUDY Physiology Department, Services Institute of Medical Sciences (SIMS), Lahore, from May to September, 2009. METHODOLOGY The study was carried out in 90 male albino mice using aceti...

An extract of Smilax china, Hemidesmus indicus and Nigella Sativa on the ratio 3:2:1, prepared by boiling in water and concentrated could completely cure cases of oral canger diagnosed by modern methods. Cytotoxic studies with the three components showed activity in Nigella sativa at a concentration of 25 microgram equivalent of the dry powder against Dalton's lymphoma ascites cells. Animal exp...