The present study was conducted to find out the antibacterial activity of aqueous and organic extracts of Nigella sativa (L.) seeds against various bacterial pathogens, namely; S. aureus, P. aeruginosa and E. coli. Plant extract along with different elicitors such as metal ions and commercial drugs was also screened to see the change in efficacy and potency of the compounds. Among different ext...

Synthesis of silver nanoparticles using seeds of Nigella sativa as reducing agent was evaluated in this study. Homogenized extract of N. sativa exposed to sunlight gave a better synthesis of nanoparticles when compared to other methods. Antibacterial activity of nanoparticles was studied against urinary tract infection (UTI) causing bacteria by disc diffusion method. Further, the silver nanopar...

Nigella sativa (NS) has been shown to have antioxidant, anti-inflammatory and antiulcer activities in different conditions. The present work was done to investigate the possible effects of Nigella sativa aqueous extracts (NS) on gastric acid secretion in isolated rat stomach. Gastric acid secretion was measured in the isolated rat stomach preparation. The results obtained in vitro experiments s...

Objectives: Nigella sativa is a medicinal plant that has long been used in traditional medicine for treating various conditions. Numerous animal studies provided evidences that the seed may elicit a broad anti-inflammatory/anti-oxidant activity. The aim of the present clinical trial was to evaluate anti-inflammatory and antioxidant properties of Nigella sativa oil in patients with rheumatoid ar...

Background: Premenstrual Syndrome (PMS) is a common problem in women. Nigella sativa has been suggested for its anti-inflammation and analgesic effects. This study was conducted to evaluate the effect of Nigella sativa oil on PMS. Methods: This double-blind clinical trial was conducted on 124 female students within the age range of 18-25 years living in the dormitories of Sabzevar University of...

Objective (s): Titanium dioxide nanoparticles (TiO2 NPs) have been recognized as biologically inert material and have been used in a multitude of applications. Nevertheless, the negative impact on the human health is not yet well understood. Aim of the work: The study attempted to evaluate the epigenetic changes of the genome, in the form of DNA methylation in liver tissue samples, resulting fr...

background: despite availability and administration of numerous antiepileptic drugs (aeds) nearly 15% of childhood epilepsy cases are resistant to treatment; in traditional medicine however nigella sativa l. (black seed) has been known for its anticonvulsant effects. materials and methods: in this double-blind clinical trial conducted on children with refractory epilepsy we administered the aqu...

results there was a statistically significant difference in vaginal itching, discharge, irritation, vulvovaginal redness and inflammation after the treatment between the two groups and much more in the study group (p ˂ 0.001). however, the culture and wet mount (with koh) results showed much improvement in the study group after treatment. conclusions the use of nigella sativa l. capsule with cl...