On November 14, 2020, Professor Dr. Friedrich Paul Magerl, a pioneer in spinal surgery and orthopedics, passed away.

INTRODUCTION The heath care system in the United States is in the midst of a transition, in large part to help accommodate an older and more medically complex population. Central to the current evolution is the reassessment of value based on the cost utility of a particular procedure compared to alternatives. The existing contribution of geriatric orthopedics to the societal burden of disease i...

Care of a trauma patient with multiple injuries can pose complex problems of prioritization. For orthopedic injuries, we prefer to perform defi nitive fi xation of all fractures in one trip to the operating room. This approach not only makes the most effi cient use of the operating room and the orthopedic surgeon, but it permits the other injuries to be treated promptly, and allows the patient ...

Wnt signaling is a ubiquitous system for intercellular communication, with multiple functions during development and in homeostasis of the body. It comprises several ligands, receptors, and inhibitors. Some molecules, such as sclerostin, appear to have bone-specific functions, and can be targeted by potential drugs. Now, ongoing clinical trials are testing these drugs as treatments for osteopor...

This revised and extended new edition retains the features that made the first edition such a popular text for pediatricians and primary care physicians: orthopedic disorders are arranged according to age of onset and also according to their frequency of occurrence, and this is supplemented with helpful guidelines for orthopedic referral. Distilling a vast wealth of the author's experience in t...

Stem cell research plays an important role in orthopedic regenerative medicine today. Current literature provides us with promising results from animal research in the fields of bone, tendon, and cartilage repair. While early clinical results are already published for bone and cartilage repair, the data about tendon repair is limited to animal studies. The success of these techniques remains in...

Interventional pain physicians are in a unique place to take advantage of regenerative medicine technology to improve patient outcomes and decrease the invasiveness of orthopedic procedural care. However, that sea of change would take significant changes to the educational system similar to those established when interventional spine was first introduced as a subspecialty. The tenets of interve...

2841 Editorial According to the latest data released by the National Bureau of Statistics, the total population of the mainland of China is 1.33 billion in 2010, including 177 million people aged 60 years or older, accounting for 13.25% of the total population, which increased to 15.53% in 2014. With the degree of growing aging population in our country, patients with musculoskeletal diseases i...