neurodegeneration is a complex and multifaceted process leading to many chronic disease states. a conventional definition implies a progressive neuronal death, which usually affects a specific population of nerve cells the vulnerability of which determines the clinical manifestations of a particular neurodegenerative disease. the neurodegenerative process is associated with many events. each ev...

enhanced oxidative stress in diabetes mellitus may contribute to the pathogenesis of diaetic complications. in this article, the stress oxidative generation has been studied in experimental diabetes by ferric reducing ability of plasma assay, a sensitive and simple method, and by other oxidative damage markers. the ferric reducing ability of plasma values as a total antioxidant capacity were si...

objective: dietary changes playmajor risk roles in oxidative stress andcardiovascular disease and modulate normal metabolic function. the present study was designed to investigate the ameliorative potential of different extracts of hemidesmus indicus to experimental high-fat diet in wistar rats, and their possible mechanism of action.  materials and methods: male wistar rats were divided into 6...

the first reaction between food components and biological tissues occurs in the oral cavity. saliva modulates the ecosystem in the oral cavity and plays a critical role in oral homeostasis. in addition, saliva is a first line of defense against free radical-mediated stress. salivary antioxidant defense mechanisms seem to be very important. in this study we discuss in detail free radicals (fr) a...

Objective(s): Exposing to stress may be associated with increased production of reactive oxygen species (ROS). Therefore, high level of oxidative stress may eventually give rise to accumulation of oxidative damage and development of numerous neurodegenerative diseases. It has been presented that brain-derived neurotrophic factor (BDNF) supports neurons against various neurodegenerative conditio...

introduction: electromagnetic fields (emfs) can influence the biological system by the formation of free radicals in cells. the emfs are able to deteriorate defense system against free radicals that leads to oxidative stress (os). lipid peroxidation process (lpo) is an index of oxidative stress, and the malandialdehyde (mda) is the final product of lpo. vitamin e is the most important antioxida...