background and objective: uterus of rat with polycystic ovary (pco) may show pathological features. we provided pathological evidence for the rat uterus with no-induced pco.    materials and methods: wistar rats (weighing 200-250 g) were kept diestrous to receive l-arginine (50 mg/kg) intraperitoneally (i.p.) for 9 days/once a day. control group solely received saline (1 ml/kg, 9 days/once per ...

Stroke is one of the leading causes mortality and disability throughout world. Recently, antioxidant therapies were attempted to reduce apoptotic cell death in cerebral ischemia animal model. To study neuroprotective properties polyphenol derived from fungal endophyte analyzed on experimental Albino rat. Polyphenols producing endophytic fungi was initially isolated seeds Moringa oleifera Lam. T...

lorazepam has in increasingly being used in our country in recent years. pharmacologically, lorazepam belongs to the benzodiazepines known for their wide neurotropic properties. there have been several studies on the side effects of the drug as stress disorders, tumors, preconvulsive activities in case of epileptic attacks, overdose, and behavioral problems, but little is known regarding the te...

conclusions the crude hydroalcoholic extract of burdock root was found to cause better outcomes in the healing process, acute inflammation, and fibrosis on the 7th, 14th, and 21st day postoperatively. objectives in this experimental study, 36 male wistar rats each weighting approximately 200 - 220 g were studied in six groups, each with 6 animals for 21 days. hydroalcoholic extract of burdock r...

introduction: alhagi camelorum belongs to the leguminosae family is used in iranian folk medicine to treat some gastric diseases. the present study was undertaken to evaluate the alhagi camelorum aqueous extract for anti-ulcer activity in rats. methods: male wistar rats were pretreated with the a. camelorum aqueous extract (150, 300 or 450 mg/kg of b.w., p.o.) before induction of gastric ulcer ...

introduction: thyroid hormones play an important role in the regulation of metabolism, maturity and reproduction. thyroid dysfunction affects almost all endocrine glands such as pituitary and testis. the aim of this study was to investigate alterations of testosterone and luteinizing hormone (lh) serum levels as well as weights of thyroid gland and testes in methimazole (mmi)-induced hypothyroi...

background; in recent years, nanoparticles have been increasingly used in industries. however, there is a serious lack of information concerning their impact on human health and the environment. this study was investigated the effect of moo3 nps on thyroid hormones in female rats. methods; in this study, 21 female wistar rats were selected and divided into three groups of untreated control, sha...

background and objectives: most antiepileptic drugs that are commonly being used in the clinic have a wide range of unwanted side effects; while some species of pistachioshave been used in the traditional medicine to treat epilepsy. the aim of the present study was to investigate the anticonvulsant effects of the hydroalcoholic extract of pistacia vera l. in pentylenetetrazole (ptz)-induced che...

background burns are still considered one of the most devastating conditions in emergency medicine affecting both genders and all age groups in developed and developing countries, resulting into physical and psychological scars and cause chronic disabilities. this study was performed to determine the healing effect of curcumin on burn wounds in rat. methods seventy female sprague-dawley 180-220...

objective: the aim of this study was to evaluate the effect of sucrose on follicular survival rate and the incidence of apoptosis in rat ovarian tissue following vitrification. methods: ovaries of approximately 5-week-old female wistar rats were divided randomly into three groups: control (non-vitrified), vi (ethylene glycol + dimethyl sulfoxide) and vii (eg + dmso + 0.25 mol/lit sucrose). vit...