background: asthma is the main reason of disability, health resource exploitation and low quality of life for those who are affected. it is estimated that nearly 300 million people in the world are suffering from asthma. studies have identified 18 genomic regions and more than 100 genes associated with asthma. among these candidate genes, il-17f plays a very interesting role in asthma. this stu...

fibroblast growth factor 2 (fgf2) serves in the uterine endometrium during estrous presenting in the bovine mammary gland which is responsible to express interferon-t (ifnt), and is an important agent to encourage the continuation of pregnancy in the ruminants. significant associations have been found between genes affected by ifnt and genes that are responsible for milk production traits. seme...

in order to study of sodium nitroprusside(snp) application effect on growth indices and water use efficiency of kidney beans cultivars(akhtar and derakhshan) under water deficit stress, an experiment was conducted in split factorial based in randomized complete block design with three replications in bu-ali sina university research field at 2012. water stress treatments included vegetative stre...

Background: Nitric oxide is a free radical that recently has emerged as a key signaling molecule in regulating important physiological processes in plants. Objective: In this work, sodium nitroprusside (SNP) was utilized as the donor of nitric oxide to investigate the effects of exogenous nitric oxide on essential oil, rosmarinic acid and antioxidant activity of in vitro-cultured Melissa offi...

Background: Since the low concentration and short-time treatment with sodium nitroprusside (SNP), a nitric oxide (NO)–donor, cause no harm to rat bone marrow mesenchymal stem cells (MSCs), we studied the impact of SNP on MSCs differentiation. Methods: MSCs were treated with 100 and 1000 µM of SNP for 1 hour in every 48 hours and after 5, 10, 15, and 21 days in osteogenic media. The viability an...

Most genetic diseases are complex, i.e. associated to combinations of SNPs rather than individual SNPs. In the last few years, this topic has often been addressed in terms of SNP-SNP interaction patterns given as expressions linked by logical operators. Methods for multiple testing in high-dimensional settings can be applied when many SNPs are considered simultaneously. However, another less we...