introduction: transplantation of bone marrow stromal cells (bmscs) or schwann cells (scs) can increase axonal regeneration in peripheral nerve injuries. based on our previous investigations, the goal of the present work was to examine the individual and synergistic effects of the two different cell types in sciatic nerve injury . we pursued to evaluate the effects of bmscs and scs co-transplant...

Rarely, sciatica is of extraspinal aetiology. By compressing the sciatic nerve, swelling of the short external rotators of the hip can cause sciatica. Uncommon anatomical relationships between the sciatic nerve and local muscles may potentiate this compressive effect. In this report, we describe the presentation of right sciatica and foot drop resulting from both extreme local constriction and ...

Address for Correspondence: Dr. Pooja Rani, Assistant Professor, Department of Anatomy, PGIMS, Rohtak, Haryana, India. Phone. +919910148979, +919034048979 and +919811370044 E-Mail: [email protected] and [email protected] *1 Assistant Professor, Department of Anatomy, PGIMS, Rohtak, Haryana, India. 2 Associate Professor, Department of Anatomy, UCMS & GTB Hospital, Delhi, India. Background...

OBJECTIVE Topical cytidine-5'-diphosphocholine (CDP-choline) improves functional recovery and promotes nerve regeneration in sciatic nerve injury in rats. The aims of this study were to test whether systemic treatment with CDP-choline was effective in improving the recovery of injured sciatic nerve, and to determine whether the cytidine and/or choline moieties of CDP-choline contribute to its ...

Schwannomas are rarely seen on the sciatic nerve and can cause sciatica. In this case report we aimed to present an unusual location of schwannoma along sciatic nerve that causes sciatica. A 60-years-old-man was admitted to us with complaints of pain on his thigh and paresthesia on his foot. Radiography of the patient revealed a solitary lesion on the sciatic nerve. The lesion was excised and t...

Sciatic nerve schwannoma is a rare disease, often misdiagnosed as sciatica in patients with no prolapsed disc the lumbar spine and negative straight leg raise test. MRI followed by biopsy investigation of choice. We present case 45-year-old male 2-year-old history right lower limb radiculopathy 2 months old ACL tear. revealed sciatic mass which was confirmed to be on FNAC. reconstruction done e...

BACKGROUND The sciatic and peroneal nerves are the most frequently injured in lower extremities, followed by tibial and femoral nerves. The aim of this study is to evaluate the functional results of acute nerve grafting in traumatic sciatic nerve injuries. METHODS A total of 9 patients with sciatic nerve defect were treated with primary nerve grafting. The mean age was 31.7 years. The etiolog...

Glycyrrhizin has a role in immune regulation in the central nervous system, but its impact on sciatic nerve injury had not previously been reported. In this study, a BALB/c mouse model of sciatic nerve injury was used to explore the role of glycyrrhizin in sciatic nerve repair and its underlying mechanism. Glycyrrhizin with intragastric gavage of 10 and 20 mg/kg weight per day (mid- and high-do...