Background: Opium, as the most widely known opioid in the world, has significant effects on reproductive organs, which can affect fertility and influence the next generation. This study was performed to investigate the effects of opium administration on histological changes and spermatogenesis indexes in the testis of adult male rats. Methods:A total of 50 adu...

Background: Saffron is widely used as a food flavor and has well known medicinal effects which have an effect on steroid and sexual hormones. The aim of present study was investigation of saffron orally administration on spermatogenesis index in stress induced rats. Materials and Methods: In present study, 160 male adult rats divided to four groups with 10 rats per each cage and with four repli...

Abstract Study question Does IGF2BP3 regulate Tcf4 mRNA stability in an N6-methyladenosine (m6A)-dependent manner, affect spermatogenesis, and lead to idiopathic non-obstructive azoospermia (iNOA)? Summary answer induces apoptosis of spermatogenic cells by regulating the m6A-dependent which turn affects spermatogenesis leading iNOA. What is known already Azoospermia most serious phenotype male ...

BACKGROUND Lepidium meyenii, known as Maca, grows exclusively in the Peruvian Andes over 4000 m altitude. It has been used traditionally to increase fertility. Previous scientific studies have demonstrated that Maca increases spermatogenesis and epididymal sperm count. The present study was aimed to investigate the effects of Maca on several fertility parameters of female mice at reproductive a...

Background: Isoniazid is an important drug in first line of treating the tuberculosis disease. This drug can lead to damages in different parts of the body such as liver and testis. Lactobacillus acidophilus and Bifidobacterium are the probiotics that have the important innate property that inhibit from passing of Isoniazid into the blood-testis-barrier. In point of spermatogenesis indexes whic...

Due to the scarcity of information about patterns of spermatogenesis in bats, this study aimed to provide information on the testicular activity of the bat Sturnira lilium along the annual seasons. Thus, a series of morphometrical and stereological analyses were made using the testes of adult S. lilium in order to achieve a better understanding of the sperm production dynamics. Light and transm...

formalin is widely used in industry and in medicine (as tissue fixative and disinfectant).it contains reactive molecules which have been known for its cytotoxic effects. to evaluate the effect of formalin exposure on the testicular tissue and sperm parameter from neonatal period through physical and sexual maturity, 28 male wister rats were assigned into two equal test and control groups. the t...