نتایج جستجو برای: Thioacetamide
تعداد نتایج: 805 فیلتر نتایج به سال:
Abstract Background and Objective: Flavonoids play an important role in non-enzymatic reaction against oxidative stress. These are polyphenolic compounds in tea structure that could be reacted with free radicals and neutralized them. In this study, we investigated the anti-oxidant impact of Camellia Sinesis on the liver of thioacetamide -injected male albino mice. Material and Methods...
Bile acid accumulation in liver with cholangiolar neoplastic lesions may occur before cholestasis is clinically detected. Whether this favors intrahepatic cholangiocarcinoma development has been investigated in this study. The E. coli RecA gene promoter was cloned upstream from Luc2 to detect in vitro direct genotoxic ability by activation of SOS genes. This assay demonstrated that bile acids w...
UNLABELLED Bile acid accumulation in liver with cholangiolar neoplastic lesions may occur before cholestasis is clinically detected. Whether this favors intrahepatic cholangiocarcinoma development has been investigated in this study. The E. coli RecA gene promoter was cloned upstream from Luc2 to detect in vitro direct genotoxic ability by activation of SOS genes. This assay demonstrated that b...
Background and Aim: The metabolism of many drugs and toxins is done in the liver and active metabolites are created during the metabolism of these substances which many of them cause liver toxicity. Therefore, the aim of the present study was to investigate the effect of curcumin on liver toxicity induced by Thioacetamide in adult male rats. Materials and Methods: In this experimental study, 4...
the ameliorative activity of aqueous extract of the flesh of dates (phoenix dactylifera l.) and ascorbic acid on thioacetamide-induced hepatotoxicity was studied in rats. sixty male rats were divided into six equal groups of 10. two groups were controls, one treated with thioacetamide and one with only distilled water. two groups received extract of flesh phoenix dactylifera and intraperitoneal...
Effects of diallyl sulfide (DAS) on thioacetamide-induced hepatotoxicity and immunotoxicity were investigated. When male Sprague-Dawley rats were treated orally with 100, 200 and 400 mg/kg of DAS in corn oil for three consecutive days, the activity of cytochrome P450 (CYP) 2E1-selective p-nitrophenol hydroxylase was dose-dependently suppressed. In addition, the activities of CYP 2B-selective be...
CdS/MoS2, an extremely efficient photocatalyst, has been extensively used in hydrogen photoproduction and pollutant degradation. CdS/MoS2 can be synthesized by a facile one-step hydrothermal process. However, the effect of the sulfur source on the synthesis of CdS/MoS2via one-step hydrothermal methods has seldom been investigated. We report herein a series of one-step hydrothermal preparations ...
To date, no attempt has been made to study alterations occurring in the amino acid profile in chronic models of thioacetamide-induced liver cirrhosis. In this work, changes in serum amino acids and proteins in rats with thioacetamide-induced liver cirrhosis are reported, together with changes in enzyme activities in the liver and serum. Seventeen female Wistar rats were used. Eight rats were gi...
Silymarin, a mixture of antihepatotoxic flavonolignans used in the treatment of liver diseases, and lactulose, a nonabsorbable synthetic disaccharide, were investigated to analyze their probable synergic and healing effects in a hepatic cirrhotic rat model. Liver damage was induced by the administration and subsequent withdrawal of thioacetamide. The significant decrease in liver enzymes and ma...
Background and Objectives: The present experimental study was aimed to investigate the effect of T. dioica flower hydroalcoholic extract on thioacetamide induced histopathological changes. Methods: Thirty adult male Wistar rats, were randomly divided into three groups of control (normal saline); negative control (thioacetamide 50 mg/kg) and group that received thioacetamide and T. dioica flo...
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