conclusions hemodialysis patients are high risk group for toxoplasmosis and should be tested periodically to prevent the dissemination of toxoplasmosis during dialysis. objectives the aim of this study was to determinate the anti- toxoplasma antibodies in hemodialysis patients of abadan and khoramshahr, southwest of iran. materials and methods sera of 150 patients (test group) aged 21 to 87 yea...

background: the diagnosis of toxoplasmosis is most critical in pregnant women who acquire infection during gestation and also in fetuses and newborns who are congenitally infected. this study described the performance of molecular and confirmatory serologic testing for toxoplasma infection in the tissues of human spontaneous aborted fetuses and their mothers' blood. materials and methods: ...

The prevalence of Toxoplasma gondii infection in free-range chickens in Jilin province, northeastern China was investigated. A total of 1095 serum samples were collected from nine administrative regions from July to October, 2012, and antibodies to T. gondii were examined by an in-house enzyme-linked immunosorbent assay (ELISA) using Toxoplasma lysate antigen (TLA). The detection results were c...

Citation Mashayekhi, Mona, Michelle M. Sandau, Ildiko R. Dunay, Eva M. Frickel, Asis Khan, Romina S. Goldszmid, Alan Sher, et al. “CD8[superscript +] Dendritic Cells Are the Critical Source of Interleukin-12 That Controls Acute Infection by Toxoplasma Gondii Tachyzoites.” Immunity 35, no. 2 (August 2011): 249–259. As Published http://dx.doi.org/10.1016/j.immuni.2011.08.008 Publisher Elsevier/Ce...

Based on a serum-free and CO,-independent culture of Toxoplasma go&ii in vitro, a simple single arrangement mass production of trophozoites of the highly virulent BK strain of this parasite was developed. Starting simultaneously, lo7 host cells (HEp-2) and 10’ Toxoplasma trophozoites were cultured in one cell-factory@ for 5 days, removing unattached cells, cell remnants and extracellular parasi...

Toxoplasmosis is a zoonotic infection caused by Toxoplasma gondii, a protozoan belonging to family Toxoplasmidae and Class Toxoplasmida(1). T. gondii was described by Nicolle and Manceaux(2) in a small North African rodent Ctenodactylus gondii. It has a world-wide distribution, but frequency of infection in man and animals varies from country to country. In general, the prevalence rate of infec...

BACKGROUND Toxoplasma gondii is the most common parasite causing latent cerebral infections in human. It has been shown that some anti-psychotic drugs are able to inhibit the proliferation of the parasite in in vitro study. There is very limited data regarding the inhibitory effect of anti-psychotics on Toxoplasma in in vivo. In this study, we evaluated anti-Toxoplasma activity of fluphenazine ...

BACKGROUND Toxoplasma gondii is an obligate intracellular protozoan parasite, capable of infecting all species of mammals including man. Congenital toxoplasmosis is more important during pregnancy for the first time. In this study we expressed and purified P43 Toxoplasma gondii tachyzoite and bradyzoite specific surface antigen. METHODS The recombinant pGEMEX-1 contained Toxoplasma P43 coding...

A possible role for Toxoplasma gondii in the etiopathogenesis of schizophrenia is supported by epidemiological studies and animal models of infection. However, recent studies attempting to link Toxoplasma to schizophrenia have yielded mixed results. We performed a nested case-control study measured serological evidence of exposure to Toxoplasma gondii in a cohort of 2052 individuals. Within thi...