The research on two-wheeled inverted pendulum (T-WIP) mobile robots or commonly known as balancing robots have gained momentum over the last decade in a number of robotic laboratories around the world (Solerno & Angeles, 2003;Grasser et al., 2002; Solerno & Angeles, 2007;Koyanagi, Lida & Yuta, 1992;Ha & Yuta, 1996; Kim, Kim & Kwak, 2003). This chapter describes the hardware design of such a rob...

An important signaling pathway to the actin cytoskeleton links the Rho family GTPase Cdc42 to the actin-nucleating Arp2/3 complex through N-WASP. Nevertheless, these previously identified components are not sufficient to mediate Cdc42-induced actin polymerization in a physiological context. In this paper, we describe the biochemical purification of Toca-1 (transducer of Cdc42-dependent actin as...

In managing a production process, choosing a proper card-based control mechanism is an important task to achieve the best performance. We present performance evaluation of the three well-known card-based production control mechanisms, KANBAN, CONWIP and Base-stock in serial production lines. We employ the theory of token transaction systems within a deterministic framework. The performance meas...

Actin-related protein 2/3 (Arp2/3) complex activation by nucleation promoting factors (NPFs) such as WASP, plays an important role in many actin-mediated cellular processes. In yeast, Arp2/3-mediated actin filament assembly drives endocytic membrane invagination and vesicle scission. Here we used genetics and quantitative live-cell imaging to probe the mechanisms that concentrate NPFs at endocy...

There exists controversy on the superiority of logistics control systems. In this paper, we propose a unified framework for analyzing and comparing of production control mechanisms. KANBAN, CONWIP and Base-stock control systems are focused on and analyzed as three well-known examples of production control systems. The periodic behavior of a token transaction system is used. By using the theory ...

In recent years, new wearable platforms and peripherals requiring unique modes of interaction have been emerging in record numbers. Watches, necklaces, glasses, even pants [1] are beginning to incorporate technology. Wearable devices also offer many new ways for users to interact; therefore, more research is needed to evaluate these novel methods of interactions. Our research focuses on proposi...

The main objective of this paper is to use simulation to study the performance of a typic:al multistage multi/ine (MSMP) pull production system having failure prone• machines, we studied the effect of the following pmduction control strategies/mechanisms namely, Independent Extended Kanban Control System (IEKCS), Simultaneous Extended Kanban Control System (SEKCS). Constant WIP (CONWIP). Hybrid...

Missense mutants that cause the immune disorder Wiskott-Aldrich Syndrome (WAS) map primarily to the Enabled/VASP homology 1 (EVH1) domain of the actin regulatory protein WASP. This domain has been implicated in both peptide and phospholipid binding. We show here that the N-WASP EVH1 domain does not bind phosphatidyl inositol-(4,5)-bisphosphate, as previously reported, but does specifically bind...

In this paper, we apply performance evaluation and capacity allocation models to support decisions in the design (or redesign) and planning of a job-shop queueing network of a metallurgical plant. Approximate parametric decomposition methods are used to evaluate system performance measures, such as the expected work-in-process (WIP) and production leadtimes. Based on these methods, optimization...

This work applies a novel model free intelligent controller to control wheeled inverted pendulums (WIPs). The main purpose of this work is to develop an adaptive output recurrent cerebellar-modelarticulation-controller (AORCMAC) for angle and position control of such a WIP without model information. Because the novel model free AORCMAC architecture captures system dynamics, it has a superior ca...