BACKGROUND Removing allergen from the indoor environment should be a primary strategy for the management and treatment of allergic disease. OBJECTIVE The aims of this study were to characterize the distribution of dog, cat, and mite allergen on hard surfaces in homes with and without pets and to evaluate the efficiency of removing allergen from hard surfaces by wiping with a dry dust cloth an...

BACKGROUND Cockroach allergy is common among inner city children with asthma, and exposure to cockroach allergen is associated with more severe disease. However, there has been little evaluation of educational approaches for controlling cockroach infestations and reducing allergen exposure. OBJECTIVE An educational intervention to reduce cockroach allergen exposure in the homes of Hispanic ch...

Exposure to indoor allergens represents a significant risk factor for allergies and asthma in several parts of the world. In Mexico, few studies have evaluated indoor allergens, including cat, dog, and mouse allergens and the factors that predict their presence. This study evaluates the main environmental and household predictors of high prenatal allergen levels and multiple allergen exposures ...

This Guideline replaces the Note for Guidance on " Allergen products " (CPMP/BWP/243/96). This Guideline lays down the quality recommendations for allergen products of biological origin, including allergen extracts derived from natural source material and allergens produced through recombinant DNA technology, used for specific immunotherapy (SIT) or in vivo diagnosis of immunoglobulin E (IgE)-m...

the aim of the present study was to characterize allergen-specific immunoglobulin e (ige) among children in fez region. eighty one children were recruited from the hospital university center of fez. all of them had completed a questionnaire before taking sera. the sera were used to measure total ige and specific data to proteins of egg's white (ewp), peanuts (pp) and gliadins (g). in last part,...

IgG4 purified from patients undergoing specific allergen immunotherapy inhibits the activities of the serum IgE in in vitro assays and is thought to reduce the symptoms of the disease. However, it is not known whether this is related to an intrinsic property of this subclass or only the allergen specificity. We tested the hypothesis that allergen specificity is the critical determinant for this...

background: melon (cucumis melo) allergy is one of the most common food allergies, characterized by oral allergy syndrome. to date, two allergen molecules, cuc m 1 and cuc m 2, have been fully characterized in melon pulp, but there are few reports about the molecular characteristics of cuc m 3. methods:the cuc m 3 cdna has been characterized by rapid amplification of cdna ends (race), which rev...

background: during the last two decades, significant advances have been made in the fields of lactococcal genetics and protein expression. lactococcus lactis (l. lactis) is an effective vector for protein expression and can be used as an antigen delivery system. hence, l. lactis is an ideal candidate for mucosal immunotherapy. profilin (che a 2), the major allergen in chenopodium album, is one ...

the relationship between mycoplasma pneumoniae (mp) infection and asthma has rarely been explored through examination of airway reactivity. the aim of this study was to determine airway reactivity changes after mp infection in children. first, 106 children were divided into four groups according to the existence of mp infection and/or asthma. then children with only mp belonged to the mp group;...

During the past 20 years, major advances have been made in understanding the molecular and cellular mechanisms of allergen tolerance in humans. The demonstration of T cell tolerance, particularly that mediated by the immune-suppressive functions of IL-10, led to a major conceptual change in this area. Currently, the known essential components of allergen tolerance include the induction of aller...