introduction rhino-orbito-cerebral mucormycosis is a progressive angioinvasive fungal disorder which almost always complicates immunocompromised patients. case presentation we described a case of fulminant rhino-orbito-cerebral mucormycosis in a 65-year-old woman, who presented with progressive neurological deficits due to involvement of orbital apex and the central nervous system by local inva...

objective: estrogen deficit following menopause results in cognitive behaviors impairment. severity of these impairments in menopause women suffer with cerebral hypo perfusion/ischemia (hi) cause the brain damage and neuronal death. this study aimed to evaluate the effects of pomegranate seed extract (pgse) on avoidance memories after permanent bilateral common carotid arteries occlusion (2ccao...

in this review the role of cerebrospinal fluid (csf) in mammalian cerebral cortex development has been highlighted. many studies have focused on the potential role of the csf in the developmental process. in particular, the cerebral cortex develops from the germinal epithelium adjacent to the csf. csf contains proteins, growth factors and other neurotrophic factors which are important for neura...

how to cite this article: amirsalary s, dehghan l, dalvand h, haghgoo h. effectiveness of neurogenesis in treating children with cerebral palsy. iran j child neurol 2012;6(2):1-8.   objective tissue-specific stem cells divide to generate different cell types for the purpose oftissue repair in the adult. the aim of this study was to detect the significance ofneurogenesis in the central nervous s...

cerebral palsy is the most common chronic motor disorder of childhood, that affecting approximately 3 infants per 1000 live-births. the risk of brain injuries that potentially cause cerebral palsy has amplified with increasing in survival rates for preterm infants. in addition cerebral palsy has a huge economic impact, to immeasurable health, social, and psychological problems that affected chi...

background: angiotensin ii (ang ii) has an important role on cerebral microcirculation however, its direct roles in terms of ischemic brain edema need to be clarified. this study evaluated the role of central ang ii by using candesartan, as an at1 receptor blocker, in the brain edema formation and blood-brain barrier (bbb) disruption caused by ischemia/reperfusion (i/r) injuries in rat. methods...

enterococci are normal inhabitants of gastrointestinal tract, being responsible for 5 to 18% of infective endocarditis and the incidence appears to be increasing. eleven patients with enterococcal endocarditis were studied. in a case series group, 10 men (average 57 years) and one woman (37 years) were studied. two patients had rheumatic heart disease, 5 patients arteriosclerotic disease and on...

aim: aquaporin4 (aqp4) is the main water channel in the brain that has important role in water transport across blood- brain- barrier. it has been proved that intracranial pressure and also expression of aqp4 increase in some disorders such as hydrocephalus, hyponatremia, cytotoxic oedema and brain tumours and drugs that can decrease the expression of this aqp can offer some treatment for these...

background: it is well known that the hippocampus, the ca1 pyramidal cells in particular, is selectively vulnerable during global cerebral ischemia. recently, it is observed that pentoxifylline has a neuroprotective effect. this study explored the pharmacological relationship between ischemia-induced cell death of the hippocampus and the efficacy of a vasodilator agent (pentoxifylline) in the p...

objective spastic cerebral palsy (cp) is one of the most difficult and disabling conditions that requires medical attention and treatment. the aim of this study was to assess the efficacy and safety of oral tizanidine in treating spasticity in children with spastic cp. materials & methods sixty children with spastic cerebral palsy were enrolled in a double-blind, placebo-controlled, randomized ...