background: pentoxifylline (ptx) is used in human for intermittent claudication and cerebral vascular disorders including cerebrovascular dementia. it also inhibits the synthesis of tumor necrosis factor-α (tnf-α), which is believed to be neurotoxic in animal models of cerebral ischemia. the objective of this study was to examine the role of ptx on ischemia/reperfusion injures in rat model of t...

the study was conducted to determine the clinical pattern and etiology of cerebral venous thrombosis in iran. records of all adult patients admitted with a clinical diagnosis and mri of cerebral venous thrombosis from 1993 through 1999 in three major hospitals of tehran, iran were reviewed. fifty patients (39 women, 11 men) aged 14 to 56 years were identified. headache the most frequent and oft...

background: leukemia inhibitory factor (lif) is a neurortophic cytokine which plays an important role in the neural cell survival. expression of lif and its receptor, lifr, in different brain regions has been demonstrated. based on evidences lif plays an important role in the modulation of neurogenesis and glial responses to injury. up-regulation of lif after central nervous system (cns) damage...

conclusions cerebral toxoplasmosis can occur outside the setting of advanced hiv immunodeficiency or drug-induced immunosuppression. this highlights the fact that it should be considered in the differential diagnosis of opportunistic infections in hiv-negative patients. case presentation a case of cerebral toxoplasmosis is reported in a healthy 39-year-old woman who was admitted to hospital wit...

objectives: most definitions equate quality of life with motor function. the aim of this study is to examine the association between gross motor function and quality of life for children with cerebral palsy. methods: in this analytical cross–sectional study, 60 children with cerebral palsy aged 4-12 were selected through convenience sampling based on inclusion criteria from occupational therapy...

conclusions if medical treatment gets started early in the course of empyema, prognosis would be excellent. besides, there was no significant difference in short- and long-term outcomes between medical or surgical interventions. objectives the aim of this study was to compare the duration of admission, duration of intravenous antibiotic therapy, time to response to treatment, and outcomes of me...

how to cite this article: dalvand h, dehghan l, feizi a, hosseini sa, amirsalari s. iran j child neurol. 2013 autumn; 7(4):12-19. abstract objective the purpose of this study was to examine the impacts of hinged and solid anklefoot orthoses (afos) on standing and walking abilities in children with spastic diplegia. materials & methods in a quasi-experimental design, 30 children with spastic dip...

conclusion following splenectomy, thrombocytosis can predispose the patients to an increase in cerebral blood velocities more than respected with anemia. but by transcranial doppler ultrasonography no evidence of significant stenosis were found in intracerebral arteries to conclude that the beta-thalassemia major patients were more prone to the development of stroke secondary to this abnormalit...

introduction: anesthetic agents, blood pressure, arterial ph and blood gases have found to influence on the pathophysiology of experimental stroke. despite, there are very few comparative studies about effects of anesthetic agents in animal model of cerebral ischemia. therefore, in this study, we investigated the effects of chloral hydrate and pentobarbital anesthesia, as comparative study, on ...

Aims:Memory deficit is the most visible symptom of cerebral ischemia. The hippocampus is sensitive against cerebral ischemia. Oxidative stress and inflammation are involved in the pathological process after cerebral ischemic injury. Paroxetine has anti-oxidative and anti-inflammatory effects. In this study the effect of paroxetine on memory deficit after cerebral ischemia was investigated. Meth...