SUDDEN CARDIAC ARREST IS THE most common lethal consequence of cardiovascular disease. Even if return of spontaneous circulation (ROSC) from cardiac arrest is achieved, approximately 60% of patients will not survive to hospital discharge. The high mortality is attributed to the postcardiac arrest syndrome, which involves global ischemiareperfusion injury, myocardial stunning, and anoxic brain i...

the mechanisms underlying cerebral vasodilatation during hypercapnia are not fully understood. to examine the role of nerves and prostaglandins in the regulation of basal blood flow and in hypercapnia-induced vasodilatation in the cerebral blood vessels of rabbit. cerebral blood flow was measured by laser doppler flow-meter in 18 nzw rabbits anesthetized with sodium pentobarbital.  tetrodetoxin...

introduction: many of study show decrease of quality of life in mothers of children with cerebral palsy due to care activity of their child but the researchers less pay attention to the decrease of mother’s quality of life in relationship with child-related factors like walking ability in children with cerebral palsy, so the aim of this study was tocomparing the quality of life of mothers with ...

background: the mechanisms underlying cerebral hypercapnic vasodilatation are not fully understood.   objective: to investigate the role of nitric oxide (no) and atp-sensitive potassium (k atp ) channels in basal blood flow regulation and hypercapnia-induced vasodilatation in rabbit cerebral blood vessels.   methods: the change in cerebral blood flow was measured by a laser doppler flowmeter in...

Purpose: To evaluate the protective effect, effective time window, and mechanism of protection sevoflurane post-conditioning late on heart muscle ischemiareperfusion (I/R) lesion in isolated rat heart.Methods: Langendorff perfusion model was established Sprague-Dawley (SD) rats. After 15 min stabilization, rats were assigned to 10 groups, based treatments given: control group (TTC), I/R group, ...

In emergency and critical care medicine, lung ischemia-reperfusion injury is a prevalent disorder, which has significant morbidity mortality. However, there still lack of effective means to block the injury. Established model mice; histological analysis scoring were helpful assess pathological in tissue; using an enzymelinked immunosorbent assay kit, expressed interleukin-6 interleukin-1 bronch...

background: nitric oxide synthase (nos) activity is increased during hypertension and cerebral ischemia. nos inactivation reduces stroke-induced cerebral injuries, but little is known about its role in blood-brain barrier (bbb) disruption and cerebral edema formation during stroke in acute hypertension. here, we investigated the role of nos inhibition in progression of edema formation and bbb d...

Background: Nitric oxide synthase (NOS) activity is increased during hypertension and cerebral ischemia. NOS inactivation reduces stroke-induced cerebral injuries, but little is known about its role in blood-brain barrier (BBB) disruption and cerebral edema formation during stroke in acute hypertension. Here, we investigated the role of NOS inhibition in progression of edema formation and BBB d...

to minimize the risk of embolic events, several protection strategies have been introduced. we have evaluated the short-term outcome of patients who underwent carotid stenting with the routine use of cerebral protection devices. in our center, 36 successful carotid stenting procedures (of 38 attempted) were performed in 37 patients (23 men; age mean [sd] 667 years). cerebral protection involv...