We evaluated the effects of cinnamon polyphenol extract on hepatic transcription factors expressions including SREBP-1c and LXR-α in rats fed high fat diet (HFD). Twenty-eight Wistar rats were allocated into four groups: (i) normal control: animals fed with normal chow; (ii) cinnamon: animals supplemented with cinnamon polyphenol; (iii) HFD: animals fed a high-fat diet; and (iv) HFD + cinnamon:...

Cinnamon has been widely recognized as hypoglycaemic agent against diabetes mellitus. This study aimed to investigate the potential histological repairing ability of damaged pancreatic tissue due to alloxaninduced diabetic rats. Diabetes was induced in 24 male Albino rats using alloxan (120mg/kg intraperitoneal). Four groups (n=6 each) received or not suspensions of cinnamon (50mg/ kg and 100mg...

Cinnamon capsules are sold as food supplements or as dietetic foods to reduce blood sugar levels in type II Diabetes mellitus, a severe chronic disease. The manufacturers recommend a daily long-term dose in the gram range although the safety of a cinnamon dose of this amount has not yet been demonstrated. Furthermore, the claimed ability of cinnamon to reduce blood sugar has not been sufficient...

The present study aims at investigating the anti-stress effects of cinnamon (Cassia zelynicum) bark extract in cold restrained stress (CRS) model. The cinnamon anti-stress effect was characterized using ulcer scoring, adrenal-gland weight, estimation of plasma glucose and cholesterol levels, as well as estimation of norepinephrine (NE) and corticosterone. Our results demonstrated that cinnamon ...

cinnamon is the bark the cinnamomi cassia that exhibits many medical properties such as anti-cancer effect and anti-diabetic effect. moreover, because of its antioxidant activity; it can be used in food industries. many studies have already reported biological and chemical properties of the cinnamon extracted essential oil such as their antimicrobial, antifungal, antimosquito, free radical scav...

The aim of this study was determine the volatile compounds, antimicrobial and antioxidant activity of the essential oils (EOs) of cinnamon (Cinnamomum verum), fenugreek seeds (Trigonella foenum greacum), ginger (Zingiber officinale) and marjoram (Origanum majorana) widely consumed in Egypt. EOs showed a great variety of compounds in their chemical compositions, Trans-cinnamyl aldehyde, terpinen...

Aims To determine the blood glucose lowering effect of cinnamon on HbA1c, blood pressure and lipid profiles in people with type 2 diabetes. Methods 58 type 2 diabetic patients (25 males and 33 females), aged 54.9 9.8, treated only with hypoglycemic agents and with an HbA1c more than 7% were randomly assigned to receive either 2g of cinnamon or placebo daily for 12 weeks. Results After intervent...

Acute and chronic consumption of alcohol can cause increased intestinal permeability and bacterial overgrowth, thereby increasing portal endotoxin levels. This barrier impairment subsequently leads to an activation of hepatic Kupffer cells and increased release of reactive oxygen species as well as of tumor necrosis factor-alpha (TNFalpha). Recent studies have suggested that cinnamon extract ma...

The antibacterial effect of aqueous garlic and cinnamon extract at five different temperatures (40 C, 60 C, 80 C, 100 C, 120 C) against five multidrug resistant bacterial isolates (2 gram negative and 3 gram positive), including Bacillus cereus, Staphylococcus aureus, Enterococcus faecalis, E. Coli and Proteus mirabilis were studied by well diffusion method. The maximum antibacterial effect of ...

Common (Cinnamomum verum, C. zeylanicum) and cassia (C. aromaticum) cinnamon have a long history of use as spices and flavouring agents. A number of pharmacological and clinical effects have been observed with their use. The objective of this study was to systematically review the scientific literature for preclinical and clinical evidence of safety, efficacy, and pharmacological activity of co...