helicobacter pylori (h. pylori) is a gram-negative bacterium that colonizes the human stomach and affects more than half of the global human population. this microorganism shows variations in its geographical distribution and causes chronic gastritis, peptic ulcer, gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. the development of these clinical entities depends on the ba...

background: accidents are the second reason for mortality and morbidity in iran. among them, brain injuries are the most important damage. clarification of the effects of brain injuries on different body systems will help physicians to prioritize their treatment strategies. in this study, the effect of pure brain trauma on the cardiovascular system and lungs 24 hours post trauma was assessed. m...

about 25-50% of graves' disease (gd) patients develop thyroid eye diseases, which is associated with inflammatory process and abnormalities in the levels of several cytokines in orbital tissues in gd.  the aim of this study was to determine the th1 and th2 serum cytokines in patients with gd with or without ophthalmopathy. serum  levels of  cytokines  and  autoantibodies  including interferon-g...

background immune cells and molecules play a vital role in initiating, maintaining, and regulating immunological homeostasis and inflammation in many pathological and physiological processes; however, the changes on expressions and functions of these cells and molecules in hepatitis b virus (hbv) infection has not been elucidated well. conclusions cxcr3-associated chemokines might contribute to...

conclusions the results of the present study show that administration of t. foenum-graecum corrects metabolic and inflammatory alterations associated with ovariectomy and has a potential for the management of menopause. objectives the purpose of this study was to examine the effect of t. foenum-graecum seed extract in reducing the metabolic and inflammatory alternations associated with menopaus...

there has been considerable inconsistency regarding the potential relationship between dyslipidemia and bone metabolism. the inflammatory stimulation through the receptor activator of the nuclear factor kappa-b ligand (rankl)/ receptor activator of the nuclear factor kappa-b (rank)/ osteoprotegerin (opg) pathway could be the infrastructural mechanism for hypercholesterolemia-induced bone loss. ...

allergic airway inflammation is characterized by elaboration of cytokines and chemokines leading to recruitment of inflammatory leukocytes, predominantly eosinophils, to the airways. granulocyte macrophage colony stimulating factor (gm-csf) is generated in the lungs of human subjects with asthma in response to allergen challenge and is necessary for the development of allergen-induced bronchial...