INTRODUCTION In England, antenatal pertussis immunization using a tetanus/low-dose diphtheria/5-component acellular-pertussis/inactivated-polio (TdaP5/IPV) vaccine was introduced in October 2012. We assessed infant responses to antigens in the maternal vaccine and to those conjugated to tetanus (TT) or the diphtheria toxin variant, CRM. METHODS Infants of 141 TdaP5/IPV-vaccinated mothers in S...

  The immunogenicity of ten different formulations of intranasal diphtheria and tetanus vaccines which containing different absorption enhancers, adjuvants and other excipients were determined in guinea pigs by the serum neutralization (SN) method. From these ten formulations, it was selected four formulations which gave significant immunogenicity in guinea pigs. In order to design the "final f...

BACKGROUND From 2005 through 2007, 3 vaccines were added to the adolescent vaccination schedule: tetanus-diphtheria-acellular pertussis (TdaP); meningococcal conjugate (MenACWY); and human papillomavirus (HPV) for girls. OBJECTIVE To assess implementation of new adolescent vaccination recommendations. METHODS Data from the 2006-2009 National Immunization Survey-Teen, an annual provider-veri...

During the Russian diphtheria epidemic of the 1990s, adults had an unexpectedly high rate of disease. A retrospective, matched case-control study was done to measure the effectiveness of one, two, or three or more doses of diphtheria toxoid against diphtheria among 40- to 49-year-old Russians. Thirty-nine diphtheria case-patients and 117 controls were studied. Previous vaccinations were include...

Objective: An outbreak of coronavirus disease 2019 (COVID-19) occurred in late 2019. A better understanding this will help us preventing and managing it. This study evaluated the risk factors clinical laboratory characteristics patients admitted to Shahid Sadoughi hospital Yazd with a diagnosis COVID-19. Methods: cross-sectional was conducted on COVID-19 May 2020, Iran. Patients’ information, i...

Evidence-based guidelines for immunization of infants, children, adolescents, and adults have been prepared by an Expert Panel of the Infectious Diseases Society of America (IDSA). These updated guidelines replace the previous immunization guidelines published in 2002. These guidelines are prepared for health care professionals who care for either immunocompetent or immunocompromised people of ...

We present a case of a four-year-old boy who succumbed to diphtheria following incomplete course of immunisation, which included diphtheria vaccine. This case report focuses on the issues of parental refusal to vaccines and the development of "halal" vaccines for the prevention of infectious diseases.

Vaccinations are recommended throughout life to prevent vaccine-preventable diseases and their sequelae. Adult vaccination coverage, however, remains low for most routinely recommended vaccines and below Healthy People 2020 targets. In October 2014, the Advisory Committee on Immunization Practices (ACIP) approved the adult immunization schedule for 2015. With the exception of influenza vaccinat...

281 Recommended for incoming undergraduate students, the book provides a quick understanding of the important terms and techniques for current DNA-related research. Its utility for medical students, however, is somewhat limited by its brevity and enormous scope. At almost $40 in hardcover, the book is far too expensive. At $16.95 in softcover, it remains somewhat less so, but may be worth the c...

BACKGROUND The Indian state of Andhra Pradesh accounted for 50% diphtheria and 3% tetanus cases reported globally during 2005. During 2003-2006, there was a rising trend of diphtheria in Hyderabad, the state capital, whereas there was no major change in trend of tetanus cases. We estimated coverage of diphtheria and tetanus vaccine among children aged <or= 6 years and immunity against these dis...