We present evidence of cross-hybridization artifact intrinsic to spotted single-dye cDNA microarrays as a result of cDNA containing 5’-end sequences of consecutive thymidine (dT) residues. These poly(dT) tracts result from the synthesis, via oligo (dT) primed reverse transcription, of expressed sequence tags (EST) cDNA from a polyadenylated mRNA template. Analysis of gene expression data from t...

Selective COX-2 inhibitors are most widely used analgesic and anti-inflammatory drugs;however, its maximal use is highly associated with various serious abnormal cardiovascularevents. Beraprost sodium (BPS), prostacyclin analogue has been shown to vasodilatory,antiplatelates, anti-inflmmatory, and antioxidant activity. The objective of the present study wasto evaluate the effect of BPS on celec...

OBJECTIVE We investigated low dose digital tomosynthesis (DT) for the evaluation of the paranasal sinus (PNS), and compared its diagnostic accuracy with a PNS radiography series (XR). MATERIALS AND METHODS We enrolled 43 patients for whom XR, PNS DT, and OMU CT were performed. We measured effective doses (EDs) of XR, DT, and OMU CT using Monte Carlo simulation software. Two radiologists perfo...

We measured just-noticeable differences in the direction and speed of motion in depth of cyclopean and monocularly visible targets. Our stimulus set comprised different combinations of (d phi/dt)/(d delta/ dt), d delta/dt, d phi/dt and delta delta, where d phi/dt was the angular frontal plane speed of the binocularly-fused target, d delta/dt was its rate of change of disparity and delta delta w...

B ecause the implantable cardioverter defibrillator (ICD) was introduced into clinical practice, insertion of these devices has typically involved defibrillation testing (DT). However, DT has never been shown to independently improve patient outcomes. The rationale for DT has always been that the induction of ventricular fibrillation (VF) immediately after ICD insertion allows the implanting te...

Average left ventricular (LV) chamber stiffness (Delta P(avg)/Delta V(avg)) is an important diastolic function index. An E-wave-based determination of Delta P(avg)/Delta V(avg) (Little WC, Ohno M, Kitzman DW, Thomas JD, Cheng CP. Circulation 92: 1933-1939, 1995) predicted that deceleration time (DT) determines stiffness as follows: Delta P(avg)/Delta V(avg) = N(pi/DT)(2) (where N is constant), ...

Multiplicative Number Theory 638 27.2 Functions . . . . . . . . . . . . . . . . . 638 27.3 Multiplicative Properties . . . . . . . . . 640 27.4 Euler Products and Dirichlet Series . . . 640 27.5 Inversion Formulas . . . . . . . . . . . . 641 27.6 Divisor Sums . . . . . . . . . . . . . . . 641 27.7 Lambert Series as Generating Functions . 641 27.8 Dirichlet Characters . . . . . . . . . . . . 642...

Power moments of Jk(t, G) = 1 √ πG ∫ ∞ −∞ |ζ( 1 2 + it+ iu)|2ke−(u/G)2 du (t ≍ T, T ε ≤ G ≪ T ), where k is a natural number, are investigated. The results that are obtained are used to show how bounds for ∫ T 0 |ζ( 1 2 + it)|2k dt may be obtained.

SUMMARY The rate of left ventricular volume change (dV/dt) is by definition left ventricular ejection rate during systole and filling rate during diastole, and in the absence of valvular regurgitation or intracardiac shunts, is equal to systolic aortic valve flow and diastolic mitral valve flow respectively. A computerized technique for the calculation of instantaneous left ventricular dV/dt fr...

The Distress Thermometer (DT) is a one-item screening measure of psychological distress in cancer patients. This study examines the operating characteristics of the DT in patients about to undergo bone marrow transplant (BMT). Patients (N=491) completed the DT, the Center for Epidemiological Studies-Depression Scale (CES-D), the State-Trait Anxiety Inventory-State Version (STAI-S), the ECOG Per...