Transition metals have been suggested to play a pivotal role in the pathogenesis of Parkinson's disease. X-ray microscopy combined with a cryogenic setup is a powerful method for elemental imaging in low concentrations and high resolution in intact cells, eliminating the need for fixation and sectioning of the specimen. Here, we performed an elemental distribution analysis in cultured primary m...

The extent to which an enzyme controls a flux has been defined as the effect on that flux of a small modulation of the activity of that enzyme divided by the magnitude of the modulation. We here show that in pathways with metabolic channelling or high enzyme concentrations and conserved moieties involving both enzymic and non-enzymic species, this definition is ambiguous; the magnitude of the c...

a new series of thiazolidinedione derivatives were synthesized. the structures of these compounds were established by means of ir, 1h-nmr and elemental analysis. all of the compounds were screened for antidiabetic activity on albino rats. most of the compounds showed significant antidiabetic activity when compared with the standard drug glibenclamide.

n-propylsalicylidene based on silica as ion exchanger (ie) was used for the separation by complexation of mn2+, co2+, ni2+, cu2+, hg2+, cr3+, fe3+, and uo22+ from their parent solutions. ie and its metal complexes are characterized by elemental analysis, electronic and infrared spectra, in addition to thermal analysis in atmospheric pressure. the mode of chelation and the proposed geometric str...

soil samples were collected from seven sites in and around the metropolitan area of mexicocity. the locations were chosen as possible sources of fugitive dusts which contribute to suspended particulate matter in the atmosphere of mexico city. x-ray fluorescence (xrf) was used to determine the concentrations of several major elements (si, k, ca, ti, mn, and fe), as well as of other trace element...

We present a framework for the rational analysis of elemental causal induction – learning about the existence of a relationship between a single cause and effect – based upon causal graphical models. This framework makes precise the intuitive distinction between causal structure and causal strength: the difference between asking whether or not a causal relationship exists, and asking how strong...

In this contribution, an effective and soft method for removal of template from nanochannels of mesoporous silica (MCM-41) is proposed. This method is based on chemically-modified solvent extraction which enhanced by means of an auxiliary organic compound, i.e. benzene sulfonamide. Template removal was performed in soft condition, i.e. in the presence of diluted sulfuric acid and at ambient tem...

Nuclear microprobe at 2 MV Tandetron accelerator of Jozef Stefan Institute (JSI) was constructed in the year 2000 with the support of IAEA Technical Cooperation Project SLO/1/004. The measuring station is equipped with instrumentation for micro-Proton-Induced-X-ray-Emission (micro-PIXE), micro-Elastic Recoil Detection Analysis (micro-ERDA), micro-Nuclear Reaction Analysis (micro-NRA), Proton Be...

ICx Technologies is currently fielding a real-time, wearable elemental carbon monitor designed to determine real-time diesel particulate levels in mines. Diesel particulates are composed primarily of elemental and organic carbon and have been found to present a health hazard. Diesel particulate levels can be particularly high in underground mines. The Mine Safety and Health Administration (MSHA...

Rapid semiquantitative elemental screening of pharmaceutical samples is described using the Agilent 7500ce ICP-MS with helium as collision gas. Polyatomic interferences are eliminated in the He pressurized cell, enabling rapid elemental profiling of pharmaceutical tablets for screening purposes. Elements which normally suffer from polyatomic interferences have been included in the semiquantitat...