The initiation of reverse transcription and nucleocapsid assembly in hepatitis B virus (HBV) depends on the specific recognition of an RNA signal (the packaging signal, epsilon) on the pregenomic RNA (pgRNA) by the viral reverse transcriptase (RT). RT-epsilon interaction in the duck hepatitis B virus (DHBV) was recently shown to require the molecular chaperone complex, the heat shock protein 90...

BACKGROUND The apolipoprotein E (APOE) epsilon 4 allele is a marker of adverse outcome following head injury and intracerebral hemorrhage. Transgenic animal data in a focal cerebral ischemia model suggest that the epsilon 4 allele increases infarct size and functional impairment. OBJECTIVE To determine if APOE genotype is associated with functional recovery from ischemic stroke. DESIGN Pros...

In 2005, Exoo posed the following question. Fix $\epsilon$ with $0\leq\epsilon<1$. Let $G_\epsilon$ be graph whose vertex set is Euclidean plane, where two vertices are adjacent iff distance between them lies in closed interval $[1-\epsilon,1+\epsilon]$. What chromatic number $\chi(G_\epsilon)$ of this graph? The case $\epsilon=0$ precisely classical ``chromatic plane'' problem. a 2018 p...

PURPOSE To investigate the concentrations of Fc epsilon receptor I (Fc epsilon RI)-bindable immunoglobulin E (IgE) in the tear fluid and the proportion of IgE-saturated cells among Fc epsilon RI-positive cells in giant papillae from vernal keratoconjunctivitis (VKC) patients. METHODS The tear fluids and giant papillae were obtained from 8 VKC patients with their informed consent. To detect th...

By defining functional defects in a congenital myasthenic syndrome (CMS), we show that two mutant residues, located in a binding site region of the acetylcholine receptor (AChR) epsilon subunit, exert opposite effects on ACh binding and suppress channel gating. Single channel kinetic analysis reveals that the first mutation, epsilon N182Y, increases ACh affinity for receptors in the resting clo...

computationally, selection of a proper numerical value for infinitesimal non archimedean epsilon in dea models has some difficulties. although there are several algorithms for selecting the proper non-archimedean epsilon, it is important to introduce methods in order to calculate the efficiency of dmus without using epsilon. one of these methods is a two-phase method, which obtains the efficien...

BACKGROUND Revision of the Task Force diagnostic criteria for arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) has increased their sensitivity for the diagnosis of early and familial forms of the disease. The epsilon wave is a major diagnostic criterion in the context of ARVC/D, which, however, remains not quantifiable and therefore may leave room for substantial subjective in...

J Lipid Res. 2006 Nov;47(11):2475-81. Protective effect of apolipoprotein E2 on coronary artery disease in African Americans is mediated through lipoprotein cholesterol. Anuurad E, Rubin J, Lu G, Pearson TA, Holleran S, Ramakrishnan R, Berglund L. Department of Medicine, University of California, Davis, CA, USA. OBJECTIVE AND METHODS: We studied the relationship of apolipoprotein E (apoE) isofo...

Precise subcellular localization is an important factor in regulation of the functions of protein tyrosine phosphatases. The non-receptor form of protein tyrosine phosphatase epsilon (cyt-PTP(epsilon)) can be found in cell nuclei, among other cellular locations, while p67 PTP(epsilon), a naturally occurring isoform which lacks the 27 N terminal residues of cyt-PTP(epsilon), is exclusively cytos...

A better understanding of the pathophysiological role of Langerhans cells (LC) in atopic diseases is dictated by the characterization of the structures involved in immunoglobulin (IgE)-binding on their cell surface. We previously reported that human LC express the high affinity receptor for IgE (Fc epsilon RI), as well as the low affinity receptor for IgE (Fc epsilon RII/CD23). In the present s...