Human Dachshund homologue 1 (DACH1) is a major component of the Retinal Determination Gene Network. Loss of DACH1 expression was found in breast, prostate, lung, endometrial, colorectal and hepatocellular carcinoma. To explore the expression, regulation and function of DACH1 in human esophageal cancer, 11 esophageal cancer cell lines, 10 cases of normal esophageal mucosa, 51 cases of different ...

Etiology of esophageal intramural pseudodiverticulosis is still unknown but several accompanying diseases have been reported, for example, reflux esophagitis, esophageal cancer, diabetes mellitus and so on. We have experienced a case of esophageal intramural pseudodiverticulosis with cancer improved by radiation therapy. In this case, there were esophageal cancer in the cervical esophagus, with...

Esophageal cancer patients are often associated with multiple primary cancers (MPC). The aim of this study is to evaluate the effect of MPC on prognosis in esophageal cancer patients treated by radiotherapy. Between 2001 and 2008, esophageal cancer patients treated by definitive radiotherapy at Gunma Cancer Center were retrospectively reviewed. Exclusion criteria were preoperative or postoperat...

Esophageal cancer is one of the most fatal diseases worldwide mainly because of its rapid progression and poor prognosis. Although the incidence of esophageal adenocarcinoma has markedly risen in North America and Europe in the past several decades, esophageal squamous cell carcinoma is still the predominant subtype of esophageal cancer, especially in China. It accounts for more than 90% of all...

telomerase activation is one of the main pathways to immortalize cancer cells. in many kinds of cancer cells, this special reverse transcriptase stabilizes and elongates telomeres and prevents telomere erosion that naturally occurs in every cell division. esophageal cancer is the fifth most frequent cause of cancer death worldwide, and is highly associated with alcohol, smoking, cultural habits...

Esophageal cancer (EC) is the eighth most common cancer and the sixth most common cause of cancer death worldwide. Esophageal squamous cell carcinoma (ESCC) and adenocarcinoma (EAC) are two major histopathological type of esophageal cancer. The incidence of EC was increased in the past 3 decades. Five-year survival of advanced cancer is still very poor, even though improved surgical techniques ...

BACKGROUND Esophageal cancer carries a poor prognosis with an overall 5-year survival of less than 20%. However, the causes of death in patients with esophageal cancer have not been well described. METHODS This nationwide, population-based cohort study included 18 229 esophageal cancer patients who were diagnosed between 1961 and 2014 in Sweden. We assessed the distribution of main causes of ...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 aim : the present study aimed to investigate the influence of histological factors on survival of patients with esophageal cancer. background : esophageal cancer is almost the common form of malignancy in the eastern world. patients and methods : through a retrospective cohort study a consecutive series of 134 patients wit...

Patients with primary head and neck cancers have a higher risk of developing esophageal cancer. The aim of this study was to investigate esophageal cancer prevalence, its risk factors (ethanol and tobacco consumption) and dietary habits in patients with head and neck cancer. Three hundred and twenty-six adults with primary head and neck cancer were followed by a retrospective observational stud...