Esophageal cancer is one of the most frequently occurring cancers in the world. Targeting therapy strategy of cancer with specific inhibitors is developing and has showed promising antitumor efficacy. It is known that mTOR is an important controller of cell growth. RAD001 (everolimus) is a specific inhibitor of mTOR that can block the mTOR signaling pathway. The purposes of this study was to ex...

This article refers to:New Co(II)-organic framework for cyanosilylation reactions and treatment effect against esophageal cancer by inhibiting cell viability, migration, invasion

esophageal cancer is the second and third most common malignancy in iranian males and females, respectively, claiming lives of approximately 5800 iranians each year. squamous cell carcinoma (scc) is presently the most common type accounting for about 90% of all esophageal cancers in iran. recent studies have shown that there is a gradual increase in the incidence of adenocarcinoma of the distal...

Patients with esophageal cancer each year can reach 400,000 people. Inefficient screening methods and worsening symptoms, patients often come late. Squamous cell carcinoma, which is the cause of cancer, has percentage 84% all incidences. So far, current strategy endoscopy biopsy. This main side effect bleeding in metaplastic area. Cellulose Sponge, Detector Esophageal Cancer (CaSPER), be used f...

The β-nitrostyrene family have been implicated for anti-cancer property. However, the pharmacological role of β-nitrostyrene in esophageal cancer remain unclear. Here, a β-nitrostyrene derivative, CYT-Rx20, was synthesized and assessed for its anti-cancer activities and underlying mechanism in esophageal cancer. CYT-Rx20 induced cytotoxicity in esophageal cancer cells by promoting apoptosis thr...

BACKGROUND Diabetes mellitus (DM) has been associated with the cancer risk. This study investigated relationship between DM and esophageal cancer using Taiwan's insurance data. METHODS We identified 549 patients with esophageal cancer newly diagnosed in 2000-2009 and randomly selected 2196 controls without any cancer, frequency matched by sex, age and diagnosis year of cases. Logistic regress...

In recent decades, decreasing trends in esophageal cancer mortality have been observed across China. We here describe esophageal cancer mortality trends in Linzhou city, a high-incidence region of esophageal cancer in China, during 1988-2010 and make a esophageal cancer mortality projection in the period 2011-2020 using a Bayesian approach. Age standardized mortality rates were estimated by dir...

Aurora-A/BTAK/STK15 gene which encodes a centrosome-associated kinase is located on chromosome 20q13.2, a highly amplified region in various human tumors. Recent studies have demonstrated the overexpression and amplification of Aurora-A in many malignant human cancers. The purpose of this study was to investigate the amplification and expression of Aurora-A in esophageal squamous cell carcinoma...

BACKGROUND Esophageal cancer is the most common carcinoma in Black South African men. A number of etiological factors have been associated with the high prevalence. OBJECTIVES The present study was undertaken to address social and environmental factors associated with the cancer in the African Black population of KwaZulu-Natal. CASE-CONTROL STUDIES AND STATISTICAL ANALYSIS: The total number o...