Background: Iran is located in Asian esophageal cancer belt, with age-standardized incidence rate (ASR) of approximately 7 per 100,000 for both men and women. To provide potential solution recommendations for achieving accurate estimations regarding the burden of the disease in Iran, we designed a study to assess the burden of esophageal cancer in Iran during 1995-2015 by collecting data from t...

We examined 170 formalin-fixed paraffin-embedded samples from esophageal squamous cell carcinoma patients. All subjects live in Mazandaran province, a region with high incidence rate of esophageal cancer and have become known as the “Asian Esophageal Cancer Belt”. Samples were tested for HPV-DNA by MY09/11 and Gp5+/6+ general primers using nested PCR. Of the 170 ESCC samples, 86 (50.6%) were ma...

background: esophageal cancer is one of the prevalent cancers in east azerbaijan province. the aims of this study are to estimate the survival rate of patients with esophageal cancer by treatment modalities and tumor location, as well as risk factors such as cigarette smoking, family history, age at diagnosis, and gender. materials and methods: in a cross-sectional study we evaluated 142 patien...

background: food consumption pattern and lack of some nutrients is known as main environmental risk factor of esophageal cancer. we investigated nutritional risk factor and food consumption pattern of people who live in high risk area in golestan province. materials and methods: we investigated food consumption pattern of more than 30 years old gonbad and kalale's people who recruited in golest...

the effects of combined radiotherapy (rt) and chemotherapy in the severity of cytogenetic alterations expressed as micronucleus (mn) in peripheral blood lymphocytes of patients treated for esophageal cancer was evaluated. to do this, blood was obtained from 23 and 15 esophageal cancer patients scheduled for chemo-radiotherapy and rt alone, respectively, before, during, and after treatment. bloo...

background: evidence shows that the mortality rate of esophageal cancer (ec) in ardabil province is among the highest worldwide. studies on the epidemiological profile of ec in ardabil are scarce. we aim to study the characteristics of ec in ardabil using data from the recently established ardabil cancer registry (acr). materials and methods: this study has been accomplished based on data colle...

loess and loess-like deposits cover large areas of golestan province of iran, a well-known region in the world for its high incidence rate of esophageal cancer (ec). despite numerous published works on the possible contributing factors for the observed high incidence rate, very little attention has been given so far to a possible link between the mineralogy of loess deposits in the region and e...

quantitative serum level measurements of gc , cp , c3 , igg , iga and 1gm were carried out on 102 patients with esophageal carcinoma following laryngectomy, in comparison with 66 healthy individuals as controls, in gonbad area, north east of iran. the procedure of radioinimuno-diffusion by standard m partigen plates was used for the measurements. a significant decrease was observed in gc level ...