Abstract Resveratrol obtained in grape seed and skin is structurally similar to a synthetic estrogen diethylstilbestrol. The endogenous estrogen, 17β-estradiol, induces cellular responses by binding the receptor alpha beta. bone fracture due decreased mineral density postmenopausal women linked reduced estrogen. adverse drug reactions of hormone replacement therapy warrant identifying unique na...

spinal cord injury (sci) is a crucial complication that results in neurons degeneration. the sci lead to triggering of secondary complications such as inflammation that in turn has a key role in neurodegeneration development. the previous studies showed that tnf-α and inos genes expression increased significantly after sci. as a consequence, these genes overexpression intensify the inflammation...

objective: to correlate serum estrogen levels with cognitive functions calculated objectively as per mini mental state examination (mmse) in the females in reproductive age group and those attaining menopause. materials and methods: this study was conducted in christian medical college and hospital, ludhiana, punjab, india. 150 subjects (100 postmenopausal females and 50 regularly menstruating ...

introduction: fennel is rich in phytoestrogens and is used for estrogen deficiency disorders. estrogens affect anxiety through neurochemical systems such as gaba-a receptors. in this study the effects of fennel on gaba-a and estrogen receptors in anxiety were investigated. methods: adult female wistar rats weighing (180±20 g) were divided into 8 groups. groups received saline, fennel (200, 500,...

introduction: obesity and visceral fat accumulation after menopause are associated with insulin resistance and cardiovascular diseases. we investigated the interactive effect of aerobic-resistance training and estrogen replacement therapy on visceral fat, omentin-1 and homa-ir in ovariectomized rats. materials and methods: fifty female wistar rats were ovariectomized (ovx) and divided into 5 gr...

Introduction: The role of estrogen in the stimulation of gonadotropin-releasing hormone (GnRH) neurons is clear. These neurons do not express estrogen alpha receptors, so other mediator neurons should be present to transmit the positive feedback effect of estrogen to the GnRH neurons. Kisspeptin neurons have an important role in the stimulation of GnRH neurons, so they can be the mediator of...

objective(s) gastric ulceration is induced by various forms of stress like surgery, ischemia and trauma. the female sex has more resistance to stress and the gastrointestinal lesions happen fewer than male sex. the purpose of this study was to evaluate the role of estradiol and progesterone on the gastric acid and pepsin levels following traumatic brain injury (tbi) induction. materials and met...