نتایج جستجو برای: fibrosis
تعداد نتایج: 110920 فیلتر نتایج به سال:
Introduction: Patients with Cystic Fibrosis have increased risk of malnutrition. Early detection of nutritional deterioration enables prompt intervention and correction. The aims of this project were to: - Define the nutritional status of CF patients in Iran and New Zealand - Compare and contrast the MacDonald Nutritional Screening tool with the Australasian guidelines for Nutrition in Cyst...
Treatment with amiodarone, a commonly prescribed antidysrhythmic agent, is associated with pulmonary fibrosis (PF) which is a commonly progressive and untreatable dieases. Caffeic acid phenethyl ester (CAPE) is a phenolic antioxidant and an active anti-inflammatory, anticancer, antimicrobial and antioxidant component of propolis (bee glue; a resinous hive product collected by honey bees). In th...
Background: TNF gene polymorphisms may influence hepatitis C virus activity. In the present study we surveyed TNF-α concentration in chronic hepatitis C patients and its association with hepatic fibrosis. Materials and methods: We investigated the association between TNF-α level and inflammatory necrosis/fibrosis grading, meanwhile, TNF association was investigated with anthropometric indices...
Background: To evaluate impact of spironolactone (S) on pulmonary toxicity of concomitant use of thoracic radiotherapy (RT) and trastuzumab (T). Materials and Methods: Eighty rats were divided into eight groups: group (G) 1 was control group; G2, G3 and G4 were RT, S and T groups; G5, G6, G7 and G8 were RT+T, T+S, RT+S and RT+T+S groups respectively. Rats were sacrificed at 6 hour, 21 and 100 ...
Background and Objectives: Citrulline (cit.) is a non-essential amino acid derived from watermelon, which affects improving glucose tolerance and lipid and energy metabolisms. The aim of this study was to investigate effects of citrulline supplementation on non-alcoholic fatty liver. Materials & Methods: In this randomized clinical trial, 50 patients with NAFLD were randomly assigned to recei...
Introduction: Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive and usually fatal lung disease of unknown etiology for which no effective treatments currently exist. In the adults type I and II pneumocytes, forms Components of the alveolar epithelial cells. In this study, we investigated the effect of thalidomide on the alveolar epithelial cells (type I and II pneumocytes) in ...
PURPOSE To investigate the utility of dynamic contrast-enhanced MRI (DCE-MRI) with Gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) for detecting liver fibrosis induced by carbon tetrachloride (CCl4) in rats. METHODS This study was approved by the institutional animal care and use committee. Liver fibrosis in rats was induced by intraperitoneal injection of 1 mL/kg 50...
nigella sativa (ns) ( ranunculaceae ) used as a protective and therapeutic traditional medicine. this study evaluates the effect of ns on inflammation-induced myocardial fibrosis, serum and tissue inflammatory markers, and oxidative stress status in male rats. fifty male wistar rats were divided into five groups: (1) control; (2) lipopolysaccharide (lps), 1 mg/kg/day; (3) lps + ns (hydroalcohol...
idiopathic pulmonary fibrosis (ipf) is a chronic lung disease of unknown etiology. recent investigations have demonstrated that the impaired immune response is a common characteristic feature of ipf. unfortunately, no definitive and effective drug treatment is available that could improve or at least inhibit the progressive course of this fatal disease. that is why one of the main priorities of...
miR-17 overexpression in cystic fibrosis airway epithelial cells decreases interleukin-8 production.
Interleukin (IL)-8 levels are higher than normal in cystic fibrosis (CF) airways, causing neutrophil infiltration and non-resolving inflammation. Overexpression of microRNAs that target IL-8 expression in airway epithelial cells may represent a therapeutic strategy for cystic fibrosis. IL-8 protein and mRNA were measured in cystic fibrosis and non-cystic fibrosis bronchoalveolar lavage fluid an...
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