Fibrosis is the pathological condition resulting in the growth of excess fibrous connective tissue in an organ or body system as a reparative or reactive process. In the field of clinical pathology, clinicians and medical scientists are endeavoring to translate experimental knowledge into effective, innovative treatments for a range of fibrotic conditions. The amelioration of whole organ functi...

A qualitative diagnosis of infertility requires attention to female and male physical abnormalities, endocrine anomalies and genetic conditions that interfere with reproduction. Many genes are likely to be involved in the complex process of reproduction. Cystic fibrosis (CF) incidence varies in different White people populations (a higher incidence of CF is observed in northern–western European...

background: hepatic steatosis is commonly observed in patients with chronic hepatitis c (chc). many studies indicate a relationship between steatosis and fibrosis progression. the aim of this study was to analyze the prevalence of hepatic steatosis and related factors in iranian chc patients.   methods: one hundred and fifteen consecutive patients with chc were enrolled which were treatment-naï...

conclusions atorvastatin may play a protective role in pulmonary fibrosis, with its effects mediated via the station’s antioxidant and anti-inflammatory properties. atorvastatin may be a potential agent for the treatment of lung injury and fibrosis. background pulmonary fibrosis is an idiopathic and chronic inflammatory interstitial lung disease, with a negligible response to available medical t...

cystic fibrosis (cf) is an autosomal recessive disease, which affects many organs as it impairs chloride channel. this study was performed to evaluate growth status and its relationship with some laboratory indices such as cholesterol (chol), triglyceride (tg), albumin and total protein in children with cf referred to pediatrics center. this study was designed as a cross-sectional study in one ...

background: cystic fibrosis (cf) is a common genetic disorder chiefly characterized by respiratory and gastrointestinal symptoms. the purpose of this study was to evaluate the clinical presentation and growth status in cf patients at the time of diagnosis and following conventional treatment. materials and methods: a cross-sectional study was conducted on 67 cf patients who enrolled for at leas...

results abnormal liver function test was detected in cf patients. as well, liver sonogram was abnormal in approximately one-third of the patients. this study showed a higher prevalence of biochemical abnormality in patients with abnormal livers ultrasonography. conclusions noninvasive paraclinical evaluation methods could be recommended in the patients with cf for early detection of silent live...

results in a group of adult patients with chb, anxa2 values were far higher than those of the control group (p = 0.001). when we assessed anxa2 levels based on fibrosis stages, serum anxa2 levels of patients with early stage fibrosis (stages 1 - 3) were significantly higher than those of patients with advanced stage fibrosis (stages 4 - 5; p = 0.001). patients and methods this study included 17...