asthma is a chronic inflammatory disorder of the airways. the stress is a factor for asthma which indicates a disorder in the function of communicational mediators of nervous and  immunological systems  such  as  neurotransmitters.  a  study  indicated  that  blood serotonin concentration increases in asthmatic patients. other study indicates that one kind of the serotonin  receptors, named 5ht...

an important step in considering of gene expression data is obtained groups of genes that have similarity patterns. biclustering methods was recently introduced for discovering subsets of genes that have coherent values across a subset of conditions. the las algorithm relies on a heuristic randomized search to find biclusters. in this paper, we introduce biclustering las algorithm and then appl...

trehalose (a-d-glucosyl-[1,1]-a-d-glucopyranoside) is involved in mechanisms that coordinate metabolism with plant growth adaptation and development. the main objective of the current work was to find out whether trehalose feeding affects the expression of two genes involved in photosynthesis: one gene coding for photosystem1 subunit h (ps1-h) and the other for the light harvesting complex b1 (...

background: transient and stable transformation of host plants are the common techniques to produce transgenic plants. however, the main drawback of stable transformation is the fact that it takes quite a long time to produce a transgenic line. while, transient gene expression is a quick method to produce recombinant proteins in plants.  objective: the main goal of the present study was to eval...

escherichia coli (e. coli) bacteria can damage dna of the gut lining cells and may encourage the development of colon cancer according to recent reports. genetic switches are specific sequence motifs and many of them are drug targets. it is interesting to know motifs and their location in sequences. at the present study, gibbs sampler algorithm was used in order to predict and find functional m...

background and purpose: mycotoxins are secondary fungal metabolites with a very high diversity that are produced by some species of aspergillus which frequently leads to contaminate food and agricultural products. recently, elimination of aflatoxin contamination in food and feed has been considered by scientists worldwide. although, the antibacterial and antifungal effects of vitamins as natura...

genetic epidemiological studies strongly suggest that additive and interactive genes, each with small effects, mediate the genetic vulnerability for schizophrenia. with the human genome working draft at hand, candidate gene (and ultimately large-scale genome-wide) association studies are gaining renewed interest in the effort to unravel the complex genetics of schizophrenia. linkage and fine ma...

background: several influential factors such as transcription factors and intracellular signaling components are involved in differentiation of stem cells into a specific lineage. p15 and p16 proteins are among these factors. accumulating evidences has introduced the epigenetic as a master regulator of these factors during lineage specification. the main objective of this study is to determine ...

conclusions this is the first report of expression of cmv cp gene in iran, which is important for the preparation of anti-cmv antibody and paving the way for the use of the virus coat protein as a nanomaterial. results the identity of the expressed protein was confirmed by immunoassays such as western blot, dot-immunobinding assay (diba) and enzyme-linked immunosorbent assay (elisa) by the use ...

background: zinc (zn) as an important trace element is essential for testicular development and spermatogenesis. molecular mechanism of zn action in the reproductive system may be related to metal binding low-molecular weight proteins, metallothioneins (mt). our objective was to determine the effect of zn on two important isoforms of mt, mt1m and mt1g genes expression on testicular sertoli cell...