we investigated neuronal uptake of noradrenaline (na) at the level of larger vessels (thoracic aorta and vena cava left renal artery and left renal vein lateral saphenous artery and lateral saphenous vein and finally central ear artery and marginal ear vein) in a model devised to mimic heart failure. the model presented here is the rabbit coronary ligation model in which myocardial infarction w...

background chronic hypoxia causes apoptosis of cardiac myocytes, however, energy production by anaerobic glycolysis protects myocardium against hypoxia injuries. aldolase a is a well-characterised key enzyme of the glycolysis pathway. ghrelin, a 28-amino-acid peptide, synthesizes in the stomach and has protective roles in cardiovascular systems and also affects metabolic pathways. objectives th...

although primary chronic hypertension (htn) is increasingly common in adolescence, secondary forms of htn are more common among children. primary htn is associated with being overweight and/or a positive family history of htn. carotid intima-media thickness, a known risk factor for atherosclerosis is frequent in both adults and children with htn and other associated cardiovascular (cv) risk fac...

background: sleep disorders are common among patients with chronic heart failure (hf), and it can have a significant effect on patients’ daily activities as well as their health. the purpose of this study was to assess sleep quality and its predictors in iranian patients with chronic hf.   methods : this cross-sectional study was conducted on a sample of 200 patients with hf in two hospitals of...

background: sleep disorders among heart failure (hf) patients negatively influence the quality of life. awareness of sleep disturbances, as one of the disturbing factors of the quality of life among hf patients, and its related factors would help health care staff to provide more comprehensive care. hence, this study was conducted to determine the quality of sleep and its related factors in hos...

acute fulminant myocarditis is a life-threatening inflammatory disease of the myocardium characterized by the rapid deterioration of the hemodynamic status of the affected individual. with prompt recognition and appropriate management, complete recovery of ventricular function is likely within a few weeks. we introduce a 28-year-old man with acute fulminant myocarditis, who experienced circulat...

background: it has been suggested that the autonomic system function and the metabolic syndrome can significantly affect patients' survival. the aim of the current study was to investigate the impact of the cardiac rehabilitation program on the autonomic system balance in patients with coronary artery disease. methods: patients with a previous diagnosis of coronary artery disease who were refer...

background: several echocardiographic markers have been introduced to assess the left ventricular (lv) mechanical dyssynchrony. we studied dyssynchrony markers and the latest lv activation site in heart failure patients with and without left bundle branch block (lbbb). methods: conventional echocardiography and tissue velocity imaging were performed for 78 patients (lv ejection fraction ≤ 35%),...

anomalous origin of the left coronary artery from the pulmonary artery (alcapa) is a rare congenital cardiac malformation. we report three cases of alcapa who survived to adulthood. the first case was a 51-year-old woman who complained of typical chest pain that was diagnosed with alcapa using cardiac catheterization and coronary computed tomographic angiography (cta). the second case was a 30-...

background & aims of the study: recent studies indicated that particulate matter can have the lung irritation, chronic lung diseases, lung tissue, etc. the aim objective of this study was to assess the mortality associated with exposure to pm10 concentrations in ilam, iran, during 2013. materials & methods: pm10 data were taken from ilam's local agency of environment (i-lae). the annual mo...