We are surrounded by a sea of microorganisms that threaten to overwhelm us. This threat is made dramatically clear by the condition of AIDS, where the immune system is crippled by a slowly progressive infection extending over a period of years. In an AIDS patient, opportunistic infectious agents, including bacteria, viruses, and fungi, take advantage of the weakened immune system to invade and ...

Introduction: Glycoprotein B (gB) is the major antigen for induction of humoral responses against human cytomegalovirus (HCMV) making it an attractive candidate for immune prophylaxis. In the present study, the humoral immune response of BALB/c mice to a truncated HCMV gB protein fused with GFP was evaluated. Methods: The truncated gB coding sequence was synthesized and cloned in pEGFPN1 eukary...

1. A modified falling ball viscometer (rolling ball viscometer) for blood and other humors is presented. It is capable of easily measuring flow properties at several stresses, as is required to define satisfactorily the properties of anomalous flow systems. At high shearing stresses, apparent specific viscosity values of 2.5 + are observed, corresponding to 2.2 +/-0.2 reported as possible with ...

SARS-CoV-2 and humoral response determinations to understand control the spread of COVID-19.

Memory formation is the most important aspect of a vaccine which can guarantee long-lasting immunity and protection. The main aim of the present study was to evaluate the memory immune responses after immunization with a mini vaccine. Mice were immunized with human immunodeficiency virus-1 P24-Nef fusion peptide and then cellular and humoral immune responses were evaluated. In order to determin...

We appreciate the response from Hsieh et al. 1 to our publication, 'Efficacy and safety of long-term treatment with lenalidomide and dexamethasone in patients with relapsed/refractory multiple myeloma'. 2 As a part of our original study, we assessed the effect of lenalidomide and dexamethasone treatment on 'humoral improvement' in multiple myeloma patients, which was defined as an increase in u...