This study first investigates the biocompatibility of self-organized TaO x nanotube arrays with different nanotube diameters fabricated by electrochemical anodization. All as-anodized TaO x nanotubes were identified to be an amorphous phase. The transition in surface wettability with TaO x nanotube diameters can be explained based on Wenzel's model in terms of geometric roughness. In vitro bioc...

Multiwalled carbon nanotubes (MWCNTs) possess unique properties rendering them a potentially useful biomaterial for neurobiological applications such as providing nanoscale contact-guidance cues for directing axon growth within peripheral nerve repair scaffolds. The in vitro biocompatibility of MWCNTs with postnatal mouse spinal sensory neurons was assessed for this application. Cell culture me...

INTRODUCTION Ventricular Assist Devices (VADs) have become a means to both preserve and prolong the lives of patients with heart failure. By providing circulatory support, VADs lessen the load of the heart. Compared to traditional medical management of heart failure, VADs have a higher patient survival rate [1]. VADs are used as both a bridge to transport as well as form of destination therapy ...

BACKGROUND This paper describes an in vitro mitochondrial test to assess the biocompatibility of haemodialysers. METHODS We tested on isolated liver mitochondria the effect of solutions obtained by an aqueous rinse of different haemodialysers (cuprophane, cellulose acetate, Hemophan, polyacrylonitrile, polymethylmethacrylate, polysulphone, polyamide). Moreover, to determine the penetration in...

Tissue engineering is a rapidly developing area that might restore, maintain or improve tissue functions. The major elements of tissue engineering are: integrate cells, scaffolds and biologically active molecules. These components act synergistically to regulate stem cell propagation and differentiation thus ensuring tissue regeneration. For evaluation of biocompatibility of enamel matrix deriv...

BACKGROUND Conventional peritoneal dialysis fluids (PDFs) have been shown to damage the mesothelial layer and are associated with the development of peritoneal fibrosis and neoangiogenesis. New-generation PDFs have therefore been developed with physiological pH and reduced levels of glucose degradation products (GDPs), precursors of advanced glycation end products (AGEs). In this work, we evalu...

Objective(s): Bacterial cellulose (BC) has applications in medical science, it is easily synthesized, economic and purer compared to plant cellulose. The present study aimed to evaluate BC, a biocompatible natural polymer, as a scaffold for the bone marrow mesenchymal stem cells (BMSCs) loaded with fisetin, a phytoestrogen.Materials and Methods: BC hydrogel scaffold was prepared from Gluconacet...

INTRODUCTION Biocompatibility ranks as one of the most important properties of dental materials. One of the criteria for biocompatibility is the absence of material toxicity to cells, according to the ISO 7405 and 10993 recommendations. Among numerous available methods for toxicity assessment; 3-dimensional Confocal Laser Scanning Microscopy (3D CLSM) imaging was chosen because it provides an a...