introduction: decayed teeth are one of the diseases of civilization. intraoral factors which interact with the others such as heredity, cultural and social factors are involved in the initiation of the disease. among social factors, health care is particularly important. the aim of the present study was to evaluate dmft, dmft and gingivitis in the first-year students of elementary, guidance and...

prohibitins are chaperone proteins highly conserved among eukaryotes. many different functions have been attributed to prohibitins depending on their tissue expression and sub-cellular localization. prohibitins play a major role in mitochondrial physiology, regulating the stability and the processing of both respiratory chain complex subunits and opa1, a mitochondrial fusion regulating protein....

background: spinal cord injury (sci) stimulates an inflammatory reaction that causes substantial secondary damage inside the injured spinal tissue. the purpose of this study was to determine the anti-inflammatory effects of epigallocatechin gallate (egcg) on traumatized spinal cord. methods: rats were randomly divided into four groups of 12 rats each as follow: sham-operated group, trauma group...

objective(s):previous research demonstrated that diabetes is one of the leading causes of learning and memory deficits. naringin, a bioflavonoid isolated from grapefruits and oranges, has potent protective effects on streptozotocin (stz)-induced diabetic rats. recently, the effects of naringin on learning and memory performances were monitored in many animal models of cognitive impairment. howev...

micrornas participate in the regulation of asthma, the goal of this study is to summarize recent researches on the roles of micrornas in the pathogenesis of asthma. a review of the english medical literatures was conducted by searching pubmed for studies concerning asthma and micrornas. the results of the present study indicate that micrornas play important roles in regulating asthma immune res...

neuro-inflammation is a growing concern that is the result of nervous tissue inflammation. some common causes that induce this problem are toxic metabolites, aging, autoimmunity, air pollution, et cetera. glial cells and a group of proteins which are called cytokines are associated in neuro-inflammation. some nervous diseases such as: parkinson's disease, alzheimer's disease and multi...

microglia is the effector cell of the innate immune system in central nervous system (cns). these cells mediate inflammatory responses in injuries. besides external factors, microglial function is also controlled by internal factors, including epigenetic regulations. mechanisms of epigenetic regulation mainly consist of dna methylation, histone modifications and use of non-coding rnas. recent s...

multiple sclerosis is an autoimmune disease of the central nervous system which its main characteristic is an inflammation and demyelination and subsequent, neural degeneration. many studies have shown that inflammation causing neuronal demyelination. ms is the most common cause of chronic neurological disability in during youth which the prognosis is that can be death. platelet activating fact...

experimental evidence suggested that sodium ferulate (sf) and oxymatrine (omt) combination had synergistic anti-inflammatory and antioxidant effects. we hypothesized that sf and omt combination treatment might have protective effects on paraquat-induced acute lung injury. in our study, the swiss mice were randomly divided into seven groups, including control, paraquat (pq), sf (6.2 mg/kg/day); ...