introduction: the principal dose-limiting factor in the use of cisplatin as an antineoplastic drug is its hepatic toxicity. this study was designed to investigate the protective role of taurine against cisplatin-induced hepatic injury. methods: male albino rats (180-220 g) were divided in to 4 groups (n=8) as follows: (1) saline-treated group (2): cisplatin-treated group (10 mg/kg ip) (3): grou...

background trauma, in addition to mortality and disability experienced by an individual, imposes direct and indirect economic and social costs on a community. traditionally, trauma is a disease of young and middle age adults, an age group which is known to be the most dynamic and economically productive of the community. increasing our knowledge concerning the etiology and patterns of trauma se...

background tendon injuries are one of the most common injuries of the hand and challenging problems in trauma surgery. they usually require surgical repair and unlike the single tendon injuries, flexor tendon injuries have higher morbidities when accompanied with nerve injuries. in the present study, i aimed to report the clinical experiences and outcomes about tendon injuries. methods a total ...

trauma continues to be the most frequent cause of death in the first four decades of life that is a main public health problem in some countries. we perform an epidemiological study of penetrating abdominal trauma (pat). we describe epidemiological of patients in pat. in a cross-sectional study we evaluated epidemiological pat admitted to emergency department in six general hospitals in tehran....

materials and methods the development of the trauma registry form began in february 2013. the variables were finalized by a team consisting of general and trauma surgeons, specialists in emergency medicine, orthopedists, neurosurgeons, and public health professionals who have special interest in trauma research. the scale was sent to 10 specialists for validation. results after assessing the sc...

in the mammalian, there are three ncx genes (ncx1, ncx2, ncx3), which their three proteins are differentially expressed in distinct regions of the central nervous system, where they might underlie different physiological and pathophysiological functions. ncx is a nine-transmembrane protein which is distributed in the brain widely. ncx operates in a bidirectional way, and exchanges ca2+ and na+ ...

a cross-sectional study with children's and parents' self-completed questionnaires was carried out to evaluate parents' ideas on children's risk-takjng behaviours and children's risky activities after school hours by age (7 and 9 years) and sex. nine elementary schools were randomly selected and 476 puphs aged seven and nine years and 471 parents were studied. most pare...

conclusions increased serum levels of interleukins 6 and 8 as a predictive marker might be associated with unfavorable clinical outcome in patients with severe tbi. results comparing the serum levels of interleukins in two groups with favorable and unfavorable clinical outcomes showed that the mean serum levels of interleukins 6 and 8 in group with favorable outcome was 85.2 ± 51.6 and 52.2 ± 3...

objective: spinal cord injury (sci) causes inflammation, deformity and cell loss. it has been shown that melissa officinalis (mo), as herbal medicine, and dexamethasone (dex) are useful in the prevention of various neurological diseases. the present study evaluated combinational effects of dex and mo on spinal cord injury. materials and methods: thirty six adult male wistar rats were used in th...