3,4-Methylendioxymethamphetamine (MDMA) has both stimulatory and hallucinogenic properties which make its psychoactive effects unique and different from those of typical psychostimulant and hallucinogenic agents. The present study investigated the effects of MDMA on extracellular dopamine (DA(ex)) and serotonin (5-HT(ex)) levels in the striatum and prefrontal cortex (PFC) using in vivo microdia...

In the two following studies from the same group, the authors used an interesting and sophisticated design of genetically modified mice that express diphtheria toxin upon Cre recombination, the expression of which itself is driven by the endogenous regulatory sequences of a target gene. This strategy thereby results in specific ablation of an entire cellular population, like kisspeptin or KISS1...

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