background: the study was designed to assess the role of preoperative neutrophil, lymphocyte, and neutrophil?lymphocyte ratio (nlr) in predicting survival outcomes of abo?incompatible liver transplantation (lt). materials and methods: we retrospectively collected the demographic and clinical  characteristics of 71 patients with end?stage liver cirrhosis following abo?incompatible lt in this stu...

antifibrotic therapies should preferentially be targeted to the activated hepatic mesenchymal cells. those cells resemble wound healing myofibroblasts and synthesize an excess of extracellular matrix (ecm) proteins. they derive from quiescent hepatic stellate cells (hsc) and portal/perivascular (myo-) fibroblasts (mf). whereas various agents have been shown to inhibit hsc/mf proliferation and c...

background maintenance of the adequate intraoperative renal perfusion is very important during orthotopic liver transplantation (olt) to prevent acute renal failure. objectives for the first time, this study was designed to survey the effects of octreotide on urine output during anesthesia for olt and early postoperative renal function. patients and methods in this randomized double-blind place...

conclusions ferric chloride is an effective haemostatic agent in controlling liver parenchymal tissue hemorrhage in an animal model. results the hemostasis time of ferric chloride concentration groups was significantly less than that of the control group (p value < 0.001). the pathologic examination showed the highest frequency of low grade inflammation based on the defined pathological grading...

background there have been very few studies evaluating the close association between excess iron and cirrhosis; however, cirrhosis could be regarded as an iron-loading disorder. objectives in this study, the goal was to show the levels of the iron content in the liver tissue in certain types of cirrhosis. patients and methods in this 7 year study (2008 - 2014), in 1000 explanted livers, the amo...

conclusions in the current study, the clinical and paraclinical signs of aflp were mostly - liver, coagulation, kidney, and hypoglycemia disorders. considering that patients mostly refer in three phases of clinical, laboratory, and complications, it is essential to evaluate the suspected ones who present clinical symptoms especially nausea, vomiting and abdominal pain. patients and methods this...

abstract background iron overload is the main transfusion related side effects in patients with transfusion dependent hemoglobinopathies. severe iron deposition in tissues leads to organ dysfunction. many organs can be affected such as heart, liver, and endocrine organs. cardiac failure and liver fibrosis are the consequent of iron overload in transfusion dependent hemoglobinopathy. magnetic re...