background liver is prone to different diseases including metabolic, congenital, infections, drug injuries, and malignancies. liver biopsy is an aggressive but definitive way to diagnose liver diseases. objectives the present study is designed to evaluate the results of liver biopsies in children referred to the pediatric gastroenterology department of nemazee hospital. materials and methods th...

conclusions the elevation of hmw-alp activity in cu treated animal suggests the occurrence of biliary disease. this may be used as a biomarker for the diagnosis of copper toxicity. results obtained data showed that with increasing administration of copper, the alp activity was elevated significantly. in comparison with the control group the elevations were between 20%-56% using gel filtration c...

pericardial hemangioma is very rare and their coincidence with other visceral hemamgiomas is exceptional. we are reporting a 72-year-old man with an incidentally discovered pericardial hemangioma during coronary artery bypass graft (cabg) and mitral valve replacement surgery and a prior history of multiple hepatic cavernous hemangiomas. this case has been reported due to its extreme rarity. to ...

review:background: liver cancer is the sixth most common cancer and the third leading cause of cancer is. the true prevalence of infection in cancer remains unknown but the incidence of these cancers in 1.7 % of all cases of cancer. the aim of this study was to examine the changes of liver cancer mortality in the population during the years 2006 to 2010.materials and methods: in this study, the...

the potential to cause tissue damage by metal ions is the matter of widespread investigation. titanium salts are widely used in industry for ceramic painting, in pharmacy for tablet coating and making chemical sunscreens and in medicine as photo catalysts with bactericidal activity. this may address the idea that the exposure to these salts could play a role in metabolic disorders. in this stud...

Background: Non-alcoholic fatty liver disease (NAFLD) is increasingly a common disease which is created by the accumulation of fat in the liver. About 20% of adults and 5% of children suffer from this disease. In some studies, half of obese children had fatty liver disease and approximately 90% of the patients with fatty liver were obese. The aim of this study was to evaluate fatty liver diseas...

acetaminophen is an analgesic and antipyretic drug, which is widely used by public and poisoning with this drug, is common. one of the most important adverse effects of acetaminophen poisoning is centrilobullar necrosis in hepatic cells, which depends on activity of microsomal cytochrome p-450 (cyp) enzymes. the aim of this investigation was to find out the protective effect of nifedipine again...

context cystic fibrosis (cf) is the most widespread autosomal recessive genetic disorder that limits life expectation amongst the caucasian population. as the median survival has increased related to early multidisciplinary intervention, other manifestations of cf have emergedespecially for the broad spectrum of hepatobiliary involvement. the present study reviews the existing literature on liv...

context celiac disease (cd) is defined as a permanent intolerance to ingested gluten. the intolerance to gluten results in immune-mediated damage of small intestine mucosa manifested by villous atrophy and crypt hyperplasia. these abnormalities resolve with initiationa gluten-free diet. evidence acquisition pubmed, ovid, and google were searched for full text articles published between 1963 and...