We have developed a large-scale integrated (LSI) complementary metal-oxide semiconductor (CMOS)-based amperometric sensor array system called "Bio-LSI" as a platform for electrochemical bio-imaging and multi-point biosensing with 400 measurement points. In this study, we newly developed a Bio-LSI chip with a light-shield structure and a mode-selectable function with the aim of extending the app...

When dealing with image databases, we often need to solve the problem of how to retrieve a desired set of images effectively and efficiently. As a representation of images, there are commonly used some high-dimensional vectors of extracted features, since in such a way the content-based image retrieval is turned into a geometric-search problem. In this article we present a case study of feature...

This paper provides a theoretical support for clustering aspect of the nonnegative matrix factorization (NMF). By utilizing the Karush-Kuhn-Tucker optimality conditions, we show that NMF objective is equivalent to graph clustering objective, so clustering aspect of the NMF has a solid justification. Different from previous approaches which usually discard the nonnegativity constraints, our appr...

Geography and geosciences deal with phenomena that span spatial scales from the molecular to planetary, temporal instantaneous billions of years. A strong reductionist tradition in sciences tempts us seek apply similar representations process-based explanations across these vast-scale ranges, usually a bottom-up perspective. However, law scale independence (LSI) states for any phenomenon exists...

PURPOSE Patient registries are used to monitor safety, examine real-world effectiveness, and may potentially contribute to comparative effectiveness research. To our knowledge, life sciences industry (LSI)-sponsored registries have not been systematically categorized. This study represents a first step toward understanding such registries over time. METHODS Studies described as registries wer...

Relative to the Gaussian measure on R, entropy and Fisher information are famously related via Gross’ logarithmic Sobolev inequality (LSI). These same functionals also separately satisfy convolution inequalities, as proved by Stam. We establish a dimension-free inequality that interpolates among these relations. Several interesting corollaries follow: (i) the deficit in the LSI satisfies a conv...

This article describes the use of Latent Semantic Indexing (LSI) and some of its variants for the TREC Legal batch task. Both folding-in and Essential Dimensions of LSI (EDLSI) appeared as if they might be successful for recall-focused retrieval on a collection of this size. Furthermore, we developed a new LSI technique, one which replaces the Singular Value Decomposition (SVD) with another tec...

We used LSI for both TREC-3 routing and adhoc tasks. For the routing tasks an LSI space was constructed using the training documents. We compared profiles constructed using just the topic words (no training) with profiles constructed using the average of relevant documents (no use of the topic words). Not surprisingly, the centroid of the relevant documents was 30% better than the topic words. ...

In general, morphological, physiological, and biochemical properties of fungal cells are drastically different among solid-state (SSC), liquid-surface (LSC), and submerged cultivation (SmC) systems. In addition to these traditional cultivation systems, a unique liquid-surface cultivation [liquid-surface immobilization (LSI)] system and interface cultivation systems [extractive liquid-surface im...