propranolol, a prototypical b-adrenergic receptor antagonist and atenolol, a cardio-selective b-antagonist are widely used in therapeutic regimens for treatment of hypertensive patients. in iran, several pharmaceutical manufacturers formulate these two b-blockers. as the formulation of a dosage form is essential for the patient's safety and drug efficacy, in this study we aimed to evaluate...

lution property of poorly water soluble drugs. In general, solid dispersion is prepared with water soluble polymer, such as polyethylene glycol (PEG) or polyvinylpyrrolidone (PVP) as carrier, to disperse the drug molecules in the polymer matrix. Recently, the porous materials were also used as a carrier to disperse the drug molecules in the pores. We have already reported that the solid dispers...