نتایج جستجو برای: mesenchymal stem cell
تعداد نتایج: 1822292 فیلتر نتایج به سال:
تغییرات بیان ژن mmp-2 و mmp-9 در سلول های بنیادی مزانشیمی مغز استخوان انسانی تحت تاثیر فاکتورهای رشد
از آن جا که سلولهای بنیادی مزانشیمی(mesenchymal stem cell,msc) توانایی تبدیل شدن به سلولهایی از رده های مختلف را در شرایط آزمایشگاه نشان داده اند. جداسازی و تکثیر به نسبت راحت و اتولوگ بودن سلولهای مزانشیم آنها را کاندید مناسب برای سلول درمانی ساخته است.اکثر مطالعات آزمایشگاهی نشان دادند که سلول های بنیادی مزانشیمی توانایی گریز از سیستم ایمنی را دارند وپاسخ های ایمنی را نیز مهار می کنند که هر د...
Abstract Background: Adipose tissue is being used word-wide as a suitable adult stem cell source the aim of this study was to examine the possibility of using different enzymes to isolate the human mesenchymal stem cells from adipose tissue. Methods: Adipose tissues which were obtained from liposuction surgery were transferred to the laboratory under sterile conditions. All samples obtained...
The melanoma cell adhesion molecule defines mesenchymal stromal cells in the human bone marrow that regenerate bone and establish a hematopoietic microenvironment in vivo. The role of the melanoma cell adhesion molecule in primary human mesenchymal stromal cells and the maintenance of hematopoietic stem and progenitor cells during ex vivo culture has not yet been demonstrated. We applied RNA in...
Mesenchymal stem cells (MSCs) as a kind of adult stem cells possess two properties of long term selfrenewal ability and multilineage differentiation potential into skeletal cell lineages. MSCs were first isolated and described from bone marrow samples. Further investigations have identified several other tissues as alternative sources for these cells. In spite of the clinical importance of MSCs...
objective(s): mesenchyme is a type of undifferentiated loose connective tissue that is derived mostly from mesoderm. recently, mesenchymal stem cells (mscs), as adult stem cells (ascs) able to divide into a variety of different cells, are of utmost importance for stem cell research. in this research, ability of the liver extract to induce differentiation of rat derived omentum tissue mesenchyma...
introduction: bone marrow (bm) is a known source of mesenchymal stem cells (mscs) that are used for cell therapy. this study attempts to identify if the wharton’s jelly (wj) is a suitable substitute for bm as a source for mscs. materials and methods: a population of human wj and bm stem cells were isolated and incubated with fluorescein conjugated antibodies for five specific msc markers. cell ...
Stem Cell Lineage Fate Highly accurate, efficient, and convenient evaluation for biomaterial-induced stem cell lineage fate is pivotal regenerative biomaterials research. In article number 2210637, Binbin Lai, Xuehui Zhang, Xuliang Deng, co-workers report MeD-P, a machine-learning-supported intelligent model, predicting human mesenchymal cell–biomaterial interaction based on RNA-seq data. This ...
Bone marrow microenvironment contains cellular and acellular compartments. The cellular compartment includes hematopoietic stem cells, mesenchymal stem cells and some other stromal cell types, while the acellular compartment is composed of scaffold proteins known as the extra cellular matrix. Direct cell-cell contact as well as cytokines secreted by mesenchymal stem cells during coculture of he...
Background and Objective: The resin secretions of Cannabis sativa are called Hashish, which has medicinal and psychological properties. The most important psychoactive compound of this plant is THC (Delta-9-Tetrahydrocannabinol), which can stimulate cannabinoid receptors in the body. This study was carried out to evaluate the effect of hydroalcoholic extract of Cannabis sativa on cell survival ...
background: stem cell therapy in small animal medicineis still in its infancy and few in vitro and in vivo research projectsregarding animal mesenchymal stem cells (mscs) have beencarried out. on the other hand, cell tracking is the first step of thecell-based therapies and is essential to recognize cell fate posttransplantation. objectives: the aim of this study was toisolate, characterize, an...
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