abstract background: autosomal dominant polycystic kidney disease (adpkd) is an inherited disorder with genetic heterogeneity. up to three loci are involved in this disease, pkdi on chromosome 16p13.3, pkd2 on 4q21, and a third locus of unknown location. methods: here we report the first molecular genetic study of adpkd and the existence oflocus heterogeneity for adpkd in the iranian population...

iron is one of the most important nutrients in the human diet. according to the high consumption of staple foods such as wheat, the deficiency of iron in these crops would lead to nutritional disorders and related complications. to identify microsatellite markers associated with wheat grain iron content,38iranian prevalent wheat genotypes were assessed using 30 pairs of genomic and est microsat...

the japanese and english white quails are widespread strains and belongs to the galliformes order, phasianidae family, coturnix genus  and japonica species. these birds are likely to be well-adapted to the hard conditions and resistance to diseases as it has attained economic importance as an agricultural species. in the current study, the genetic variation of japanese and english white  quail ...

autosomal dominant polycystic kidney disease (adpkd) is the most common genetic nephropathy, which is characterized by replacement of renal parenchyma with multiple cysts. in iran, the disease prevalence within the chronic hemodialysis patient population is approximately 8-10%. so far, three genetic loci have been identified to be responsible for adpkd. little information is available concernin...

The shape of the mandible was compared by morphometric methods to ascertain the genetic differences between two substrains of F344 rats, F344/DuCrlCrlj and F344/NSlc. Since these two substrains are clearly different in survival and the incidence of age associated disorders; thus, some genetic differences are suggested to be present between them. Although previous microsatellite analysis did not...

We discovered variable modes of parental care in a breeding population of color-banded Veeries (Catharus fuscescens), a Nearctic-Neotropical migratory songbird, long thought to be socially monogamous, and performed a multi-locus DNA microsatellite analysis to estimate parentage and kinship in a sample of 37 adults and 21 offspring. We detected multiple mating in both sexes, and four modes of pa...

To optimize the labeling and visualization of PCR products we tested different variables, including deoxynucleotide concentration and ratio, dilution of labeled product, number of PCR cycles, and use of one-step or nested labeling protocols. Labeling was achieved using a fixed amount of labeled dATP, whose relative specific activity was varied by adding increasing amounts of cold dATP. Optimal ...

We examined the effects of inbreeding on the performance of wood frog (Rana sylvatica) larvae in the field and in the laboratory. We used microsatellite analysis to establish the parentage and degree of inbreeding of the larvae. Two different estimators of inbreeding were used. The first was based on average multilocus heterozygosity, and the second was based on a molecular relatedness estimato...

body weight (bw) and carcass traits are complex and important economic traits that may benefit from the implementation of mas. the objective of the current study was to identify qtl associated with bw and carcass traits in an experimental half-sib cross of japanese quails selected for bw at 4 weeks of age. body weight and carcass traits were measured in the f2 population. total f2 individuals a...